Optoacoustic imaging of blood vessels

I. Patrikeev, H. P. Brecht, Y. Y. Petrov, I. Y. Petrova, Donald Prough, Rinat Esenaliev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optoacoustic imaging, a novel noninvasive modality, combines the advantages of optical methods and the ultrasound technique. The optoacoustic technique is based on tissue irradiation with nanosecond laser pulses and detection of ultrasound waves generated due to thermo-elastic expansion. Using a modified Monte Carlo technique and solution of wave equation for velocity potential, we modeled optoacoustic signals from cylindrical blood vessels with varying oxygenation and varying total hemoglobin concentration. A specially designed computer code was used for reconstruction of images of absorbed energy in the blood vessels and surrounding tissues. Then we performed a set of experiments with our optoacoustic system and phantoms that simulate blood vessels such as veins and arteries at depths of up to 2 cm. The optoacoustic signals from the phantoms were used for reconstruction of 2-D cross-section images and correlated well with geometry and optical properties of the phantoms. The obtained data suggest that the developed optoacoustic imaging approach can be used for accurate mapping of blood oxygenation and hemoglobin concentration in blood vessels.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6513
DOIs
StatePublished - 2007
EventMedical Imaging 2007: Ultrasonic Imaging and Signal Processing - San Diego, CA, United States
Duration: Feb 18 2007Feb 19 2007

Other

OtherMedical Imaging 2007: Ultrasonic Imaging and Signal Processing
CountryUnited States
CitySan Diego, CA
Period2/18/072/19/07

Fingerprint

Photoacoustic effect
Blood vessels
Imaging techniques
Oxygenation
Hemoglobin
Ultrasonics
Tissue
Wave equations
Laser pulses
Blood
Optical properties
Irradiation
Geometry
Experiments

Keywords

  • Filtered back-projection
  • Monte Carlo simulation
  • Optoacoustic monitoring

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Patrikeev, I., Brecht, H. P., Petrov, Y. Y., Petrova, I. Y., Prough, D., & Esenaliev, R. (2007). Optoacoustic imaging of blood vessels. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6513). [65130R] https://doi.org/10.1117/12.711176

Optoacoustic imaging of blood vessels. / Patrikeev, I.; Brecht, H. P.; Petrov, Y. Y.; Petrova, I. Y.; Prough, Donald; Esenaliev, Rinat.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6513 2007. 65130R.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Patrikeev, I, Brecht, HP, Petrov, YY, Petrova, IY, Prough, D & Esenaliev, R 2007, Optoacoustic imaging of blood vessels. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6513, 65130R, Medical Imaging 2007: Ultrasonic Imaging and Signal Processing, San Diego, CA, United States, 2/18/07. https://doi.org/10.1117/12.711176
Patrikeev I, Brecht HP, Petrov YY, Petrova IY, Prough D, Esenaliev R. Optoacoustic imaging of blood vessels. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6513. 2007. 65130R https://doi.org/10.1117/12.711176
Patrikeev, I. ; Brecht, H. P. ; Petrov, Y. Y. ; Petrova, I. Y. ; Prough, Donald ; Esenaliev, Rinat. / Optoacoustic imaging of blood vessels. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6513 2007.
@inproceedings{fe9a64739ff54c09bec6c3f143c37f17,
title = "Optoacoustic imaging of blood vessels",
abstract = "Optoacoustic imaging, a novel noninvasive modality, combines the advantages of optical methods and the ultrasound technique. The optoacoustic technique is based on tissue irradiation with nanosecond laser pulses and detection of ultrasound waves generated due to thermo-elastic expansion. Using a modified Monte Carlo technique and solution of wave equation for velocity potential, we modeled optoacoustic signals from cylindrical blood vessels with varying oxygenation and varying total hemoglobin concentration. A specially designed computer code was used for reconstruction of images of absorbed energy in the blood vessels and surrounding tissues. Then we performed a set of experiments with our optoacoustic system and phantoms that simulate blood vessels such as veins and arteries at depths of up to 2 cm. The optoacoustic signals from the phantoms were used for reconstruction of 2-D cross-section images and correlated well with geometry and optical properties of the phantoms. The obtained data suggest that the developed optoacoustic imaging approach can be used for accurate mapping of blood oxygenation and hemoglobin concentration in blood vessels.",
keywords = "Filtered back-projection, Monte Carlo simulation, Optoacoustic monitoring",
author = "I. Patrikeev and Brecht, {H. P.} and Petrov, {Y. Y.} and Petrova, {I. Y.} and Donald Prough and Rinat Esenaliev",
year = "2007",
doi = "10.1117/12.711176",
language = "English (US)",
isbn = "081946631X",
volume = "6513",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Optoacoustic imaging of blood vessels

AU - Patrikeev, I.

AU - Brecht, H. P.

AU - Petrov, Y. Y.

AU - Petrova, I. Y.

AU - Prough, Donald

AU - Esenaliev, Rinat

PY - 2007

Y1 - 2007

N2 - Optoacoustic imaging, a novel noninvasive modality, combines the advantages of optical methods and the ultrasound technique. The optoacoustic technique is based on tissue irradiation with nanosecond laser pulses and detection of ultrasound waves generated due to thermo-elastic expansion. Using a modified Monte Carlo technique and solution of wave equation for velocity potential, we modeled optoacoustic signals from cylindrical blood vessels with varying oxygenation and varying total hemoglobin concentration. A specially designed computer code was used for reconstruction of images of absorbed energy in the blood vessels and surrounding tissues. Then we performed a set of experiments with our optoacoustic system and phantoms that simulate blood vessels such as veins and arteries at depths of up to 2 cm. The optoacoustic signals from the phantoms were used for reconstruction of 2-D cross-section images and correlated well with geometry and optical properties of the phantoms. The obtained data suggest that the developed optoacoustic imaging approach can be used for accurate mapping of blood oxygenation and hemoglobin concentration in blood vessels.

AB - Optoacoustic imaging, a novel noninvasive modality, combines the advantages of optical methods and the ultrasound technique. The optoacoustic technique is based on tissue irradiation with nanosecond laser pulses and detection of ultrasound waves generated due to thermo-elastic expansion. Using a modified Monte Carlo technique and solution of wave equation for velocity potential, we modeled optoacoustic signals from cylindrical blood vessels with varying oxygenation and varying total hemoglobin concentration. A specially designed computer code was used for reconstruction of images of absorbed energy in the blood vessels and surrounding tissues. Then we performed a set of experiments with our optoacoustic system and phantoms that simulate blood vessels such as veins and arteries at depths of up to 2 cm. The optoacoustic signals from the phantoms were used for reconstruction of 2-D cross-section images and correlated well with geometry and optical properties of the phantoms. The obtained data suggest that the developed optoacoustic imaging approach can be used for accurate mapping of blood oxygenation and hemoglobin concentration in blood vessels.

KW - Filtered back-projection

KW - Monte Carlo simulation

KW - Optoacoustic monitoring

UR - http://www.scopus.com/inward/record.url?scp=35148817062&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35148817062&partnerID=8YFLogxK

U2 - 10.1117/12.711176

DO - 10.1117/12.711176

M3 - Conference contribution

SN - 081946631X

SN - 9780819466310

VL - 6513

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -