Optoacoustic laser monitoring of cooling and freezing of tissues

K. V. Larin, I. V. Larina, Massoud Motamedi, Rinat Esenaliev

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Real-time monitoring of cooling and freezing of tissues, cells, and other biological objects with a high spatial and time resolution, which is necessary for selective destruction of cancer and benign tumours during cryotherapy, as well as for preventing any damage to the structure and functioning of biological objects in cryobiology, is considered. The optoacoustic method, based on the measurement and analysis of acoustic waves induced by short laser pulses, is proposed for monitoring the cooling and freezing of the tissue. The effect of cooling and freezing on the amplitude and time profile of acoustic signals generated in real tissues and in a model object is studied. The experimental results indicate that the optoacoustic laser technique can be used for real-time monitoring of cooling and freezing of biological objects with a submillimeter spatial resolution and a high contrast.

Original languageEnglish (US)
Pages (from-to)953-958
Number of pages6
JournalQuantum Electronics
Volume32
Issue number11
DOIs
StatePublished - Nov 2002

Fingerprint

Photoacoustic effect
Freezing
freezing
Tissue
Cooling
cooling
Lasers
Monitoring
lasers
Cryotherapy
spatial resolution
acoustics
destruction
Tumors
Laser pulses
tumors
Acoustics
cancer
Acoustic waves
damage

Keywords

  • Freezing and cooling of tissues
  • Optical properties
  • Optoacoustics
  • Real-time monitoring

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Physics and Astronomy (miscellaneous)

Cite this

Optoacoustic laser monitoring of cooling and freezing of tissues. / Larin, K. V.; Larina, I. V.; Motamedi, Massoud; Esenaliev, Rinat.

In: Quantum Electronics, Vol. 32, No. 11, 11.2002, p. 953-958.

Research output: Contribution to journalArticle

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