Optoacoustic monitoring of blood hemoglobin concentration: A pilot clinical study

Irina Y. Petrova, Rinat Esenaliev, Yuriy Y. Petrov, Hans Peter F Brecht, Christer H. Svensen, Joel Olsson, Donald J. Deyo, Donald Prough

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

The optoacoustic technique is noninvasive, has high spatial resolution, and potentially can be used to measure the total hemoglobin concentration ([THb]) continuously and accurately. We performed in vitro measurements in blood and in vivo tests in healthy volunteers. Our clinical protocol included rapid infusion of intravenous saline to simulate rapid change in the [THb] during fluid therapy or surgery. Optoacoustic measurements were made from the wrist area overlying the radial artery for more than 1 h. The amplitude of the optoacoustic signal generated in the radial artery closely followed the [THb] measured directly in concurrently collected blood samples.

Original languageEnglish (US)
Pages (from-to)1677-1679
Number of pages3
JournalOptics Letters
Volume30
Issue number13
DOIs
StatePublished - Jul 1 2005

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hemoglobin
blood
arteries
wrist
surgery
therapy
spatial resolution
fluids
high resolution

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Optoacoustic monitoring of blood hemoglobin concentration : A pilot clinical study. / Petrova, Irina Y.; Esenaliev, Rinat; Petrov, Yuriy Y.; Brecht, Hans Peter F; Svensen, Christer H.; Olsson, Joel; Deyo, Donald J.; Prough, Donald.

In: Optics Letters, Vol. 30, No. 13, 01.07.2005, p. 1677-1679.

Research output: Contribution to journalArticle

Petrova, IY, Esenaliev, R, Petrov, YY, Brecht, HPF, Svensen, CH, Olsson, J, Deyo, DJ & Prough, D 2005, 'Optoacoustic monitoring of blood hemoglobin concentration: A pilot clinical study', Optics Letters, vol. 30, no. 13, pp. 1677-1679. https://doi.org/10.1364/OL.30.001677
Petrova IY, Esenaliev R, Petrov YY, Brecht HPF, Svensen CH, Olsson J et al. Optoacoustic monitoring of blood hemoglobin concentration: A pilot clinical study. Optics Letters. 2005 Jul 1;30(13):1677-1679. https://doi.org/10.1364/OL.30.001677
Petrova, Irina Y. ; Esenaliev, Rinat ; Petrov, Yuriy Y. ; Brecht, Hans Peter F ; Svensen, Christer H. ; Olsson, Joel ; Deyo, Donald J. ; Prough, Donald. / Optoacoustic monitoring of blood hemoglobin concentration : A pilot clinical study. In: Optics Letters. 2005 ; Vol. 30, No. 13. pp. 1677-1679.
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