Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses

Alioune Gaye, Oumar Faye, Cheikh T. Diagne, Ousmane Faye, Diawo Diallo, Scott Weaver, Amadou A. Sall, Mawlouth Diallo

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. Methods: We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. Results: The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Conclusion: Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.

Original languageEnglish (US)
Pages (from-to)1355-1359
Number of pages5
JournalTropical Medicine and International Health
Volume19
Issue number11
DOIs
StatePublished - Nov 1 2014

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Senegal
Dengue
Aedes
Culicidae
Diptera
Viruses
Infection
Urban Population
Real-Time Polymerase Chain Reaction
Leg
Serogroup
Population

Keywords

  • Aedes aegypti
  • Dakar
  • Dengue serotypes 1 and 3
  • Kedougou
  • Oral susceptibility
  • Senegal

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Parasitology
  • Medicine(all)

Cite this

Oral susceptibility of Aedes aegypti (Diptera : Culicidae) from Senegal for dengue serotypes 1 and 3 viruses. / Gaye, Alioune; Faye, Oumar; Diagne, Cheikh T.; Faye, Ousmane; Diallo, Diawo; Weaver, Scott; Sall, Amadou A.; Diallo, Mawlouth.

In: Tropical Medicine and International Health, Vol. 19, No. 11, 01.11.2014, p. 1355-1359.

Research output: Contribution to journalArticle

Gaye, Alioune ; Faye, Oumar ; Diagne, Cheikh T. ; Faye, Ousmane ; Diallo, Diawo ; Weaver, Scott ; Sall, Amadou A. ; Diallo, Mawlouth. / Oral susceptibility of Aedes aegypti (Diptera : Culicidae) from Senegal for dengue serotypes 1 and 3 viruses. In: Tropical Medicine and International Health. 2014 ; Vol. 19, No. 11. pp. 1355-1359.
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