Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses

Alioune Gaye; Oumar Faye; Cheikh T. Diagne; Ousmane Faye; Diawo Diallo; Scott C. Weaver; Amadou A. Sall; Mawlouth Diallo

doi:10.1111/tmi.12373

Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses

Alioune Gaye, Oumar Faye, Cheikh T. Diagne, Ousmane Faye, Diawo Diallo, Scott C. Weaver, Amadou A. Sall, Mawlouth Diallo

Microbiology And Immunology

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Objective: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. Methods: We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. Results: The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Conclusion: Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.

Original language	English (US)
Pages (from-to)	1355-1359
Number of pages	5
Journal	Tropical Medicine and International Health
Volume	19
Issue number	11
DOIs	https://doi.org/10.1111/tmi.12373
State	Published - Nov 1 2014

Keywords

Aedes aegypti
Dakar
Dengue serotypes 1 and 3
Kedougou
Oral susceptibility
Senegal

ASJC Scopus subject areas

Parasitology
Public Health, Environmental and Occupational Health
Infectious Diseases

Access to Document

10.1111/tmi.12373

Cite this

@article{94d49f6000084c0caef8d68569d6e334,

title = "Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses",

abstract = "Objective: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. Methods: We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. Results: The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Conclusion: Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.",

keywords = "Aedes aegypti, Dakar, Dengue serotypes 1 and 3, Kedougou, Oral susceptibility, Senegal",

author = "Alioune Gaye and Oumar Faye and Diagne, {Cheikh T.} and Ousmane Faye and Diawo Diallo and Weaver, {Scott C.} and Sall, {Amadou A.} and Mawlouth Diallo",

note = "Publisher Copyright: {\textcopyright} 2014 John Wiley & Sons Ltd.",

year = "2014",

month = nov,

day = "1",

doi = "10.1111/tmi.12373",

language = "English (US)",

volume = "19",

pages = "1355--1359",

journal = "Tropical Medicine and International Health",

issn = "1360-2276",

publisher = "Wiley-Blackwell",

number = "11",

}

TY - JOUR

T1 - Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses

AU - Gaye, Alioune

AU - Faye, Oumar

AU - Diagne, Cheikh T.

AU - Faye, Ousmane

AU - Diallo, Diawo

AU - Weaver, Scott C.

AU - Sall, Amadou A.

AU - Diallo, Mawlouth

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Objective: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. Methods: We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. Results: The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Conclusion: Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.

AB - Objective: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. Methods: We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. Results: The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Conclusion: Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.

KW - Aedes aegypti

KW - Dakar

KW - Dengue serotypes 1 and 3

KW - Kedougou

KW - Oral susceptibility

KW - Senegal

UR - http://www.scopus.com/inward/record.url?scp=84907896082&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907896082&partnerID=8YFLogxK

U2 - 10.1111/tmi.12373

DO - 10.1111/tmi.12373

M3 - Article

C2 - 25134541

AN - SCOPUS:84907896082

SN - 1360-2276

VL - 19

SP - 1355

EP - 1359

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

IS - 11

ER -

Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this