Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses

Alioune Gaye, Oumar Faye, Cheikh T. Diagne, Ousmane Faye, Diawo Diallo, Scott C. Weaver, Amadou A. Sall, Mawlouth Diallo

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Objective: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. Methods: We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. Results: The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Conclusion: Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.

Original languageEnglish (US)
Pages (from-to)1355-1359
Number of pages5
JournalTropical Medicine and International Health
Volume19
Issue number11
DOIs
StatePublished - Nov 1 2014

Keywords

  • Aedes aegypti
  • Dakar
  • Dengue serotypes 1 and 3
  • Kedougou
  • Oral susceptibility
  • Senegal

ASJC Scopus subject areas

  • Parasitology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses'. Together they form a unique fingerprint.

  • Cite this