Organised haematoma of the maxillary sinus: Pathophysiological differences suggesting a new aetiological hypothesis

S. Urata, M. Ohki, T. Tsutsumi, S. Kikuchi

Research output: Contribution to journalArticlepeer-review

Abstract

Background and objectives: Organised haematomas of the maxillary sinus are rare, non-neoplastic, haemorrhagic lesions which can extend into the nasal cavity and/or the other paranasal sinuses. This study aimed to investigate the pathology of maxillary sinus organised haematoma, and also proposes a new aetiological hypothesis based on the observed pathology. Methods: Biopsies, computed tomography, magnetic resonance imaging and post-surgical histopathological examination of resected specimens were carried out. Conclusion: Distinct pathological differences were observed between the basal and peripheral portions of organised haematomas. We propose that an organised haematoma originates from the exudation of blood components between vascular endothelial cells. As a result, the basal portion consists of aggregated, dilated vessels around the natural ostium of the maxillary sinus. In addition, pseudovessels, without endothelial cells, arise from endocapillary vessels within the haematoma. Exudation of additional blood components from the pseudovessels advances the growth of the organised haematoma.

Original languageEnglish (US)
Pages (from-to)519-524
Number of pages6
JournalJournal of Laryngology and Otology
Volume127
Issue number5
DOIs
StatePublished - May 2013
Externally publishedYes

Keywords

  • Hematoma
  • Maxillary Sinus
  • Pathology

ASJC Scopus subject areas

  • Otorhinolaryngology

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