Organochlorine pesticide residues in mothers' milk: A source of toxic chemicals in suckling infants

N. Ramakrishnan, B. S. Kaphalia, T. D. Seth, N. K. Roy

Research output: Contribution to journalArticle

Abstract

A total of 24 samples of mother's milk collected during the first week of lactation from four major cities in India (Karnal, Bangalore, Calcutta and Bombay) were analysed for the estimation of organochlorine pesticides (OCPs). α-HCH, p,p'-DDE, and p,p'-DDT were generally the main contaminants. The average total 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) levels stand at 0.05, 0.11, 0.19 and 0.22 p.p.m. (whole milk basis) in the samples from Bangalore, Calcutta, Karnal and Bombay respectively. In the same order total hexachlorocyclohexane (HCH) levels were around 0.01, 0.03, 0.03 and 0.05 p.p.m. Wide variations among OCP levels observed in the present study have no relation with the fat content of the various samples. The samples from Calcutta and Bombay showed significantly high levels of OCPs. The daily intake of total HCH and DDT residues calculated for the suckling infant was significantly higher in the present study when compared with the WHO recommended value.

Original languageEnglish (US)
Pages (from-to)7-12
Number of pages6
JournalHuman Toxicology
Volume4
Issue number1
StatePublished - 1985
Externally publishedYes

Fingerprint

Pesticide Residues
DDT
Poisons
Lindane
Milk
Mothers
Pesticides
Dichlorodiphenyl Dichloroethylene
Lactation
India
Fats
Impurities

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Organochlorine pesticide residues in mothers' milk : A source of toxic chemicals in suckling infants. / Ramakrishnan, N.; Kaphalia, B. S.; Seth, T. D.; Roy, N. K.

In: Human Toxicology, Vol. 4, No. 1, 1985, p. 7-12.

Research output: Contribution to journalArticle

@article{171ca38c8fe748998d6cf7b43f27bedf,
title = "Organochlorine pesticide residues in mothers' milk: A source of toxic chemicals in suckling infants",
abstract = "A total of 24 samples of mother's milk collected during the first week of lactation from four major cities in India (Karnal, Bangalore, Calcutta and Bombay) were analysed for the estimation of organochlorine pesticides (OCPs). α-HCH, p,p'-DDE, and p,p'-DDT were generally the main contaminants. The average total 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) levels stand at 0.05, 0.11, 0.19 and 0.22 p.p.m. (whole milk basis) in the samples from Bangalore, Calcutta, Karnal and Bombay respectively. In the same order total hexachlorocyclohexane (HCH) levels were around 0.01, 0.03, 0.03 and 0.05 p.p.m. Wide variations among OCP levels observed in the present study have no relation with the fat content of the various samples. The samples from Calcutta and Bombay showed significantly high levels of OCPs. The daily intake of total HCH and DDT residues calculated for the suckling infant was significantly higher in the present study when compared with the WHO recommended value.",
author = "N. Ramakrishnan and Kaphalia, {B. S.} and Seth, {T. D.} and Roy, {N. K.}",
year = "1985",
language = "English (US)",
volume = "4",
pages = "7--12",
journal = "Human and Experimental Toxicology",
issn = "0960-3271",
publisher = "SAGE Publications Inc.",
number = "1",

}

TY - JOUR

T1 - Organochlorine pesticide residues in mothers' milk

T2 - A source of toxic chemicals in suckling infants

AU - Ramakrishnan, N.

AU - Kaphalia, B. S.

AU - Seth, T. D.

AU - Roy, N. K.

PY - 1985

Y1 - 1985

N2 - A total of 24 samples of mother's milk collected during the first week of lactation from four major cities in India (Karnal, Bangalore, Calcutta and Bombay) were analysed for the estimation of organochlorine pesticides (OCPs). α-HCH, p,p'-DDE, and p,p'-DDT were generally the main contaminants. The average total 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) levels stand at 0.05, 0.11, 0.19 and 0.22 p.p.m. (whole milk basis) in the samples from Bangalore, Calcutta, Karnal and Bombay respectively. In the same order total hexachlorocyclohexane (HCH) levels were around 0.01, 0.03, 0.03 and 0.05 p.p.m. Wide variations among OCP levels observed in the present study have no relation with the fat content of the various samples. The samples from Calcutta and Bombay showed significantly high levels of OCPs. The daily intake of total HCH and DDT residues calculated for the suckling infant was significantly higher in the present study when compared with the WHO recommended value.

AB - A total of 24 samples of mother's milk collected during the first week of lactation from four major cities in India (Karnal, Bangalore, Calcutta and Bombay) were analysed for the estimation of organochlorine pesticides (OCPs). α-HCH, p,p'-DDE, and p,p'-DDT were generally the main contaminants. The average total 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) levels stand at 0.05, 0.11, 0.19 and 0.22 p.p.m. (whole milk basis) in the samples from Bangalore, Calcutta, Karnal and Bombay respectively. In the same order total hexachlorocyclohexane (HCH) levels were around 0.01, 0.03, 0.03 and 0.05 p.p.m. Wide variations among OCP levels observed in the present study have no relation with the fat content of the various samples. The samples from Calcutta and Bombay showed significantly high levels of OCPs. The daily intake of total HCH and DDT residues calculated for the suckling infant was significantly higher in the present study when compared with the WHO recommended value.

UR - http://www.scopus.com/inward/record.url?scp=0021993130&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021993130&partnerID=8YFLogxK

M3 - Article

C2 - 3988308

VL - 4

SP - 7

EP - 12

JO - Human and Experimental Toxicology

JF - Human and Experimental Toxicology

SN - 0960-3271

IS - 1

ER -