Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil.

Translated title of the contribution: Outbreak of classical fever of dengue caused by serotype 2 in Araguaiana, Tocantins, Brazil

P. F. Vasconcelos, E. S. Travassos da Rosa, J. F. Travassos da Rosa, R. B. de Freitas, N. Dégallier, S. G. Rodrigues, A. P. Travassos da Rosa

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

We report the first outbreak of dengue fever caused by dengue 2 (DEN 2) in Araguaina, Tocantins State. Four hundred people of 74 families, living at S. João, Araguaina Sul and Neblina districts were questioned and then bled, in order to obtain sera to test for anti-dengue antibodies. If a person was sick, a small quantity of blood was collected for virus isolation. The main clinical picture of disease was characterized by fever, headache, myalgias, arthralgias and skin rash. Were obtained 1,105 (56 females and 45 males of Culex quinquefasciatus and 567 females and 437 males of Aedes aegypti) mosquitoes from larvae collected in Araguaina. The females of Aedes aegypti obtained from larvae were allowed to feed on 8 febrile patients. The diagnosis of infection was made by both virus isolation into Aedes albopictus (C6/36) cells, and serology, by Hemagglutination-inhibition (HI) and IgM capture ELISA (MAC ELISA). No virus was isolated from mosquitoes. Although five strains of DEN 2 were obtained from humans, and another 111 infections were diagnosed serologically (IgM positive). The positivity rate of the samples was 27.75% (111 of 400), while that of the families was 66.2% (45 of 72), where at least one member of the each family was infected. It was also detected 26.1% of asymptomatic infections. All age groups were affected. Therefore, the infection was more frequent in females (33.5%) than males (23.8%).(ABSTRACT TRUNCATED AT 250 WORDS)

Original languagePortuguese
Pages (from-to)141-148
Number of pages8
JournalRevista do Instituto de Medicina Tropical de Sao Paulo
Volume35
Issue number2
StatePublished - Mar 1993
Externally publishedYes

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Dengue
Disease Outbreaks
Brazil
Aedes
Viruses
Culicidae
Larva
Immunoglobulin M
Fever
Infection
Enzyme-Linked Immunosorbent Assay
Culex
Asymptomatic Infections
Myalgia
Arthralgia
Hemagglutination
Serology
Exanthema
Headache
Anti-Idiotypic Antibodies

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Vasconcelos, P. F., Travassos da Rosa, E. S., Travassos da Rosa, J. F., de Freitas, R. B., Dégallier, N., Rodrigues, S. G., & Travassos da Rosa, A. P. (1993). Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil. Revista do Instituto de Medicina Tropical de Sao Paulo, 35(2), 141-148.

Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil. / Vasconcelos, P. F.; Travassos da Rosa, E. S.; Travassos da Rosa, J. F.; de Freitas, R. B.; Dégallier, N.; Rodrigues, S. G.; Travassos da Rosa, A. P.

In: Revista do Instituto de Medicina Tropical de Sao Paulo, Vol. 35, No. 2, 03.1993, p. 141-148.

Research output: Contribution to journalArticle

Vasconcelos, PF, Travassos da Rosa, ES, Travassos da Rosa, JF, de Freitas, RB, Dégallier, N, Rodrigues, SG & Travassos da Rosa, AP 1993, 'Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil.', Revista do Instituto de Medicina Tropical de Sao Paulo, vol. 35, no. 2, pp. 141-148.
Vasconcelos PF, Travassos da Rosa ES, Travassos da Rosa JF, de Freitas RB, Dégallier N, Rodrigues SG et al. Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil. Revista do Instituto de Medicina Tropical de Sao Paulo. 1993 Mar;35(2):141-148.
Vasconcelos, P. F. ; Travassos da Rosa, E. S. ; Travassos da Rosa, J. F. ; de Freitas, R. B. ; Dégallier, N. ; Rodrigues, S. G. ; Travassos da Rosa, A. P. / Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil. In: Revista do Instituto de Medicina Tropical de Sao Paulo. 1993 ; Vol. 35, No. 2. pp. 141-148.
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