Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment

Jacob F. Gomez; Ian G. Bemis; Ismaila Shittu; Gregory C. Gray; Kristen K. Coleman

doi:10.1016/j.onehlt.2025.101211

Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment

Jacob F. Gomez
, Ian G. Bemis
, Ismaila Shittu
, Gregory C. Gray
, Kristen K. Coleman

Internal Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3–4 months post recovery.

Original language	English (US)
Article number	101211
Journal	One Health
Volume	21
DOIs	https://doi.org/10.1016/j.onehlt.2025.101211
State	Published - Dec 2025

Keywords

Avian influenza virus
Cats
Cross-species transmission
Felines
One health
Zoonosis

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/j.onehlt.2025.101211

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title = "Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment",

abstract = "We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3–4 months post recovery.",

keywords = "Avian influenza virus, Cats, Cross-species transmission, Felines, One health, Zoonosis",

author = "Gomez, \{Jacob F.\} and Bemis, \{Ian G.\} and Ismaila Shittu and Gray, \{Gregory C.\} and Coleman, \{Kristen K.\}",

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language = "English (US)",

volume = "21",

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AU - Gomez, Jacob F.

AU - Bemis, Ian G.

AU - Shittu, Ismaila

AU - Gray, Gregory C.

AU - Coleman, Kristen K.

PY - 2025/12

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AB - We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3–4 months post recovery.

KW - Avian influenza virus

KW - Cats

KW - Cross-species transmission

KW - Felines

KW - One health

KW - Zoonosis

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JO - One Health

JF - One Health

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ER -

Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment

Abstract

Keywords

ASJC Scopus subject areas

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