Outcome of renal transplant in hereditary gelsolin amyloidosis

Mohammadali Mohajel Shoja, Mohammad R. Ardalan, R. Shane Tubbs, Sari Kiuru-Enari

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Amyloid nephropathy is an unusual manifestation of hereditary gelsolin amyloidosis and may present with proteinuria and progressive renal failure. We report the first case of renal transplantation in a patient with hereditary gelsolin amyloidosis complicated by end-stage renal disease. The patient was a 44-year-old man from the Northwest of Iran who had undergone hemodialysis for 1 year. He finally received a living, unrelated renal transplant. During a 6-year posttransplant period, the patient maintained stable allograft function without proteinuria. No significant infectious or cardiac complications were noted. Although a definite conclusion cannot be reached with a single case, this report may indicate that renal transplantation can be successfully attempted in patients with hereditary gelsolin amyloidosis and amyloid nephropathy. Renal transplantation has been performed in various hereditary, primary, and secondary amyloidoses. A brief review of this topic is presented.

Original languageEnglish (US)
Pages (from-to)370-372
Number of pages3
JournalAmerican Journal of the Medical Sciences
Volume337
Issue number5
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Fingerprint

Familial Amyloidosis
Gelsolin
Kidney Transplantation
Transplants
Kidney
Proteinuria
Amyloid
Iran
Chronic Kidney Failure
Renal Insufficiency
Allografts
Renal Dialysis

Keywords

  • Hereditary gelsolin amyloidosis
  • Kidney
  • Nephropathy
  • Transplant

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Outcome of renal transplant in hereditary gelsolin amyloidosis. / Mohajel Shoja, Mohammadali; Ardalan, Mohammad R.; Tubbs, R. Shane; Kiuru-Enari, Sari.

In: American Journal of the Medical Sciences, Vol. 337, No. 5, 01.01.2009, p. 370-372.

Research output: Contribution to journalArticle

Mohajel Shoja, M, Ardalan, MR, Tubbs, RS & Kiuru-Enari, S 2009, 'Outcome of renal transplant in hereditary gelsolin amyloidosis', American Journal of the Medical Sciences, vol. 337, no. 5, pp. 370-372. https://doi.org/10.1097/MAJ.0b013e3181a4199c
Mohajel Shoja, Mohammadali ; Ardalan, Mohammad R. ; Tubbs, R. Shane ; Kiuru-Enari, Sari. / Outcome of renal transplant in hereditary gelsolin amyloidosis. In: American Journal of the Medical Sciences. 2009 ; Vol. 337, No. 5. pp. 370-372.
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