Outcomes of Bacteremia in Burn Patients Involved in Combat Operations Overseas

Roseanne A. Ressner, Clinton K. Murray, Matthew E. Griffith, Mark S. Rasnake, Duane R. Hospenthal, Steven Wolf

Research output: Contribution to journalArticle

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Abstract

Background: Burn patients constitute approximately 5% of casualties injured in support of US military operations in Iraq (Operation Iraqi Freedom [OIF]) and Afghanistan (Operation Enduring Freedom [OEF]). Since the onset of these conflicts, there have been numerous casualties infected with multidrug-resistant bacteria. It is currently unclear if bacteremia with these multidrug-resistant organisms in OIF/OEF burn casualties is associated with increased mortality. Study Design: We performed a retrospective cohort study of all patients admitted to the US Army Institute of Surgical Research burn center from January 2003 to May 2006 to evaluate bacteremia in our burn-patient population. Results: One hundred twenty-nine of 1,258 patients admitted to the burn center became bacteremic during their hospitalization. Of these, 92 had bacteremia with the top four pathogens in our burn center, ie, Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter calcoaceticus-baumannii complex, and Staphylococcus aureus. Presence of any bacteremia was associated with mortality and increased ventilator days. Bacteremia with K pneumoniae was associated with a statistically increased mortality and a prolonged ventilator course relative to all other pathogens. Conclusions: Casualties of OIF/OEF with burn injuries did not have different outcomes than patients whose burns were not associated with military operations. Bacteremia, especially with a multidrug-resistant organism, causes increased mortality in burn patients. Of all the pathogens causing bacteremia, K pneumonia appears to have the greatest impact on mortality.

Original languageEnglish (US)
Pages (from-to)439-444
Number of pages6
JournalJournal of the American College of Surgeons
Volume206
Issue number3
DOIs
StatePublished - Mar 1 2008
Externally publishedYes

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2003-2011 Iraq War
Bacteremia
Afghan Campaign 2001-
Burn Units
Mortality
Mechanical Ventilators
Burns
Pneumonia
Acinetobacter calcoaceticus
Afghanistan
Acinetobacter baumannii
Iraq
Klebsiella pneumoniae
Pseudomonas aeruginosa
Staphylococcus aureus
Hospitalization
Cohort Studies
Retrospective Studies
Bacteria
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery

Cite this

Outcomes of Bacteremia in Burn Patients Involved in Combat Operations Overseas. / Ressner, Roseanne A.; Murray, Clinton K.; Griffith, Matthew E.; Rasnake, Mark S.; Hospenthal, Duane R.; Wolf, Steven.

In: Journal of the American College of Surgeons, Vol. 206, No. 3, 01.03.2008, p. 439-444.

Research output: Contribution to journalArticle

Ressner, Roseanne A. ; Murray, Clinton K. ; Griffith, Matthew E. ; Rasnake, Mark S. ; Hospenthal, Duane R. ; Wolf, Steven. / Outcomes of Bacteremia in Burn Patients Involved in Combat Operations Overseas. In: Journal of the American College of Surgeons. 2008 ; Vol. 206, No. 3. pp. 439-444.
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