Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)

Keyphrases

• Oxidative Damage 100%
• Methyl-CpG 100%
• Methyl-CpG Binding Domain 100%
• Methyl-CpG-binding Protein 2 (MeCP2) 100%
• Methyl-binding Proteins 100%
• 5-hydroxymethylcytosine (5hmC) 75%
• 8-oxoguanine 50%
• Methylation Pattern 50%
• Duplex 50%
• Protein-DNA Complex 25%
• Protein-protein Interaction 25%
• Guanine 25%
• Gene Regulation 25%
• Methylation 25%
• Oligonucleotides 25%
• Protein Family 25%
• Protein Binding 25%
• Oxidative DNA Damage 25%
• Recognition Sequence 25%
• Binding Affinity 25%
• Order of Magnitude 25%
• Chromatin Organization 25%
• Protein Recognition 25%
• Human Tumors 25%
• Epigenetic Modification 25%
• Gene Silencing 25%
• CpG Dinucleotide 25%
• Gene Activity 25%
• Associated Genes 25%
• CpG Sites 25%
• Chromatin Condensation 25%
• Histone-modifying Enzymes 25%
• Patterning Genes 25%
• Selective Placement 25%

Neuroscience

• Methyl CpG Binding Protein 100%
• Methyl-CpG-Binding Domain 100%
• Methyl CpG Binding Protein 2 100%
• Methylation 100%
• 5-Hydroxymethylcytosine 50%
• Protein Binding 25%
• Deoxyribonucleoprotein 25%
• Dinucleotide 25%
• Cytosine 25%
• Protein-Protein Interaction 25%
• Gene Control 25%
• Binding Affinity 25%
• Histone 25%
• Protein Family 25%
• Gene Activity 25%
• Guanine 25%
• 8-Oxoguanine 25%
• CpG Site 25%
• Chromatin Condensation 25%
• Oligonucleotide 25%
• Gene Inactivation 25%

Biochemistry, Genetics and Molecular Biology

• Binding Protein 100%
• Methyl-CpG-Binding Domain 100%
• Methylation 57%
• 5-Hydroxymethylcytosine 28%
• Binding Affinity 14%
• Protein-Protein Interaction 14%
• Transcription 14%
• Oligonucleotide 14%
• Gene Control 14%
• Epigenetics 14%
• Protein Family 14%
• Gene Activity 14%
• Recognition Sequence 14%
• CpG Site 14%
• Chromatin Condensation 14%
• Histone-Modifying Enzymes 14%
• Gene Inactivation 14%
• Cytosine 14%
• Guanine 14%