Abstract
Inflammation primarily due to immune cell invasion towards the neoplasm is one of the characteristics of cancer milieu. While oxidative stress is one of the mediators of chronic inflammation, it can also activate inflammasomes which have been linked to immunosuppression, angiogenesis, and activation of survival pathways all leading to the development of neoplasm. And polyphenols and flavonoids, which are potent antioxidants, have the potential to protect against inflammasome-associated cancer.
Original language | English (US) |
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Title of host publication | Handbook of Oxidative Stress in Cancer |
Subtitle of host publication | Mechanistic Aspects |
Publisher | Springer Nature |
Pages | 2435-2447 |
Number of pages | 13 |
Volume | 3 |
ISBN (Electronic) | 9789811594113 |
ISBN (Print) | 9789811594106 |
DOIs | |
State | Published - Jan 1 2022 |
Externally published | Yes |
Keywords
- Flavonoids
- Free radicals
- Inflammation
- Neoplasm
- Tumor
ASJC Scopus subject areas
- General Medicine
- General Biochemistry, Genetics and Molecular Biology