Oyster ciliary inhibition by cystic fibrosis factor

Barbara H. Bowman; Lillian H. Lockhart; Michael L. McCombs

doi:10.1126/science.164.3877.325

Oyster ciliary inhibition by cystic fibrosis factor

Barbara H. Bowman, Lillian H. Lockhart, Michael L. McCombs

Pediatrics

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Abstract

Ciliary inhibition in oysters serves as an assay in identifying a serum factor in cystic fibrosis patients and heterozygotes. Serums from 47 patients with cystic fibrosis and 19 heterozygotes caused ciliary cessation within 35 minutes, whereas serums from only 2 of 64 individuals without cystic fibrosis inhibited ciliary activity within this time.

Original language	English (US)
Pages (from-to)	325-326
Number of pages	2
Journal	Science
Volume	164
Issue number	3877
DOIs	https://doi.org/10.1126/science.164.3877.325
State	Published - 1969

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title = "Oyster ciliary inhibition by cystic fibrosis factor",

abstract = "Ciliary inhibition in oysters serves as an assay in identifying a serum factor in cystic fibrosis patients and heterozygotes. Serums from 47 patients with cystic fibrosis and 19 heterozygotes caused ciliary cessation within 35 minutes, whereas serums from only 2 of 64 individuals without cystic fibrosis inhibited ciliary activity within this time.",

author = "Bowman, \{Barbara H.\} and Lockhart, \{Lillian H.\} and McCombs, \{Michael L.\}",

year = "1969",

doi = "10.1126/science.164.3877.325",

language = "English (US)",

volume = "164",

pages = "325--326",

journal = "Science",

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publisher = "American Association for the Advancement of Science",

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TY - JOUR

T1 - Oyster ciliary inhibition by cystic fibrosis factor

AU - Bowman, Barbara H.

AU - Lockhart, Lillian H.

AU - McCombs, Michael L.

PY - 1969

Y1 - 1969

N2 - Ciliary inhibition in oysters serves as an assay in identifying a serum factor in cystic fibrosis patients and heterozygotes. Serums from 47 patients with cystic fibrosis and 19 heterozygotes caused ciliary cessation within 35 minutes, whereas serums from only 2 of 64 individuals without cystic fibrosis inhibited ciliary activity within this time.

AB - Ciliary inhibition in oysters serves as an assay in identifying a serum factor in cystic fibrosis patients and heterozygotes. Serums from 47 patients with cystic fibrosis and 19 heterozygotes caused ciliary cessation within 35 minutes, whereas serums from only 2 of 64 individuals without cystic fibrosis inhibited ciliary activity within this time.

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U2 - 10.1126/science.164.3877.325

DO - 10.1126/science.164.3877.325

M3 - Article

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AN - SCOPUS:0014683047

SN - 0036-8075

VL - 164

SP - 325

EP - 326

JO - Science

JF - Science

IS - 3877

ER -

Oyster ciliary inhibition by cystic fibrosis factor

Abstract

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