Pancreatic neoplasms in pregnancy

diagnosis, complications, and management.

Casey A. Boyd, Jaime Benarroch-Gampel, Gokhan Kilic, Edward J. Kruse, Sharon M. Weber, Taylor S. Riall

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Neoplasms of the pancreas during pregnancy are rare, with less than 25 cases of benign and malignant tumors reported in the literature. We present three unique cases of pancreatic tumors occurring during pregnancy--one mucinous cystic neoplasm and two adenocarcinomas. We review the literature regarding pancreatic neoplasms during pregnancy and discuss the diagnosis, complications, and management of these tumors. Magnetic resonance imaging and ultrasound are the imaging modalities of choice in pregnancy. In patients with benign or premalignant tumors, surgical resection may be postponed until the second trimester. In symptomatic patients, or if there is a concern for intrauterine growth restriction, urgent surgical intervention should be performed. With malignant tumors, the benefit of delaying surgery must be balanced with the risk of maternal disease progression. Termination of the pregnancy should be discussed when a malignant tumor is diagnosed during the first trimester. Pancreatic tumors diagnosed during the third trimester may be resected after delivery. If malignant, early delivery of the fetus and subsequent maternal operation can be considered at appropriate fetal maturity. When these tumors occur during pregnancy, they present a diagnostic and treatment dilemma, with variation in treatment based on gestational age and patient preference.

Original languageEnglish (US)
Pages (from-to)1064-1071
Number of pages8
JournalJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
Volume16
Issue number5
DOIs
StatePublished - May 2012
Externally publishedYes

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Pregnancy Complications
Pancreatic Neoplasms
Pregnancy
Neoplasms
Mothers
Patient Preference
Third Pregnancy Trimester
Second Pregnancy Trimester
First Pregnancy Trimester
Gestational Age
Disease Progression
Ultrasonography
Adenocarcinoma
Fetus
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pancreatic neoplasms in pregnancy : diagnosis, complications, and management. / Boyd, Casey A.; Benarroch-Gampel, Jaime; Kilic, Gokhan; Kruse, Edward J.; Weber, Sharon M.; Riall, Taylor S.

In: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, Vol. 16, No. 5, 05.2012, p. 1064-1071.

Research output: Contribution to journalArticle

Boyd, Casey A. ; Benarroch-Gampel, Jaime ; Kilic, Gokhan ; Kruse, Edward J. ; Weber, Sharon M. ; Riall, Taylor S. / Pancreatic neoplasms in pregnancy : diagnosis, complications, and management. In: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2012 ; Vol. 16, No. 5. pp. 1064-1071.
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