TY - JOUR
T1 - Panel 7
T2 - Treatment and comparative effectiveness research
AU - Marchisio, Paola
AU - Chonmaitree, Tasnee
AU - Leibovitz, Eugene
AU - Lieberthal, Allan
AU - Lous, Jorgen
AU - Mandel, Ellen
AU - McCormick, David
AU - Morris, Peter
AU - Ruohola, Aino
PY - 2013/4
Y1 - 2013/4
N2 - Background and Objectives. Otitis media (OM) is one of the most common reasons for antibiotic treatment in children. Controversies regarding antibiotic treatment for OM have accumulated in the past decade, and there seem to be more dilemmas than certainties. The objectives of this article are to provide the state-of-the art review on achievements in treatment of all different stages of OM, including acute otitis media (AOM), otitis media with effusion (OME), and chronic suppurative otitis media, and to outline the future research areas. Data Sources. PubMed, Ovid Medline, the Cochrane Database, and Clinical Evidence (BMJ Publishing). Review Methods. All types of articles related to OM treatment published in English between January 2007 and June 2011 were identified. A total of 286 articles related to OM treatment were reviewed by the panel members; 114 relevant quality articles were identified and summarized. Results. New evidence emerged on beneficial results of antibiotic treatment, compared with observation of AOM in young children who were diagnosed based on stringent criteria. In OME, the main results were related to a nonsignificant benefit of adenoidectomy versus tympanostomy tube placement alone in the treatment of chronic OME in younger children. Other modalities of OM treatment were studied and described herein. Conclusions and Implications for Practice. Significant progress has been made in advancing the knowledge on the treatment of OM. Areas of potential future research have been identified and outlined.
AB - Background and Objectives. Otitis media (OM) is one of the most common reasons for antibiotic treatment in children. Controversies regarding antibiotic treatment for OM have accumulated in the past decade, and there seem to be more dilemmas than certainties. The objectives of this article are to provide the state-of-the art review on achievements in treatment of all different stages of OM, including acute otitis media (AOM), otitis media with effusion (OME), and chronic suppurative otitis media, and to outline the future research areas. Data Sources. PubMed, Ovid Medline, the Cochrane Database, and Clinical Evidence (BMJ Publishing). Review Methods. All types of articles related to OM treatment published in English between January 2007 and June 2011 were identified. A total of 286 articles related to OM treatment were reviewed by the panel members; 114 relevant quality articles were identified and summarized. Results. New evidence emerged on beneficial results of antibiotic treatment, compared with observation of AOM in young children who were diagnosed based on stringent criteria. In OME, the main results were related to a nonsignificant benefit of adenoidectomy versus tympanostomy tube placement alone in the treatment of chronic OME in younger children. Other modalities of OM treatment were studied and described herein. Conclusions and Implications for Practice. Significant progress has been made in advancing the knowledge on the treatment of OM. Areas of potential future research have been identified and outlined.
KW - Antibiotics
KW - Otitis media
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=84878832607&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878832607&partnerID=8YFLogxK
U2 - 10.1177/0194599812465397
DO - 10.1177/0194599812465397
M3 - Article
C2 - 23536528
AN - SCOPUS:84878832607
SN - 0194-5998
VL - 148
SP - E102-E121
JO - Otolaryngology - Head and Neck Surgery (United States)
JF - Otolaryngology - Head and Neck Surgery (United States)
IS - 4 SUPPL.
ER -