Past and Present: A Review of Antenatal Corticosteroids and Recommendations for Late Preterm Birth Steroids

C. Luke Dixon; Gloria Too; George R. Saade; Cynthia Gyamfi-Bannerman

doi:10.1055/s-0038-1653944

Past and Present: A Review of Antenatal Corticosteroids and Recommendations for Late Preterm Birth Steroids

C. Luke Dixon, Gloria Too, George R. Saade, Cynthia Gyamfi-Bannerman

Obstetrics & Gynecology

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Since 1972, the beneficial neonatal effects of antenatal corticosteroids (ACSs) have been repeatedly demonstrated in pregnancies at risk of preterm birth before 34 weeks' gestation. While ACS utilization before 34 weeks has been high since the 1990s, knowledge gaps regarding the risks and benefits of ACS continue to exist. Recent evidence has been published regarding the benefit of ACS in the late preterm period. This review addresses the evidence and knowledge gaps for ACS use before and after 34 weeks' gestation. We also provide recommendations for ACS use in the late preterm period.

Original language	English (US)
Pages (from-to)	1241-1250
Number of pages	10
Journal	American Journal of Perinatology
Volume	35
Issue number	13
DOIs	https://doi.org/10.1055/s-0038-1653944
State	Published - May 23 2018

Keywords

antenatal corticosteroids
betamethasone
dexamethasone
fetal
late preterm steroids
maturity

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1055/s-0038-1653944

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title = "Past and Present: A Review of Antenatal Corticosteroids and Recommendations for Late Preterm Birth Steroids",

abstract = "Since 1972, the beneficial neonatal effects of antenatal corticosteroids (ACSs) have been repeatedly demonstrated in pregnancies at risk of preterm birth before 34 weeks' gestation. While ACS utilization before 34 weeks has been high since the 1990s, knowledge gaps regarding the risks and benefits of ACS continue to exist. Recent evidence has been published regarding the benefit of ACS in the late preterm period. This review addresses the evidence and knowledge gaps for ACS use before and after 34 weeks' gestation. We also provide recommendations for ACS use in the late preterm period.",

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AB - Since 1972, the beneficial neonatal effects of antenatal corticosteroids (ACSs) have been repeatedly demonstrated in pregnancies at risk of preterm birth before 34 weeks' gestation. While ACS utilization before 34 weeks has been high since the 1990s, knowledge gaps regarding the risks and benefits of ACS continue to exist. Recent evidence has been published regarding the benefit of ACS in the late preterm period. This review addresses the evidence and knowledge gaps for ACS use before and after 34 weeks' gestation. We also provide recommendations for ACS use in the late preterm period.

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Past and Present: A Review of Antenatal Corticosteroids and Recommendations for Late Preterm Birth Steroids

Abstract

Keywords

ASJC Scopus subject areas

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