Pathogenesis and Clinical and Economic Consequences of Postoperative Ileus

Michael G. Doorly, Anthony J. Senagore

    Research output: Contribution to journalReview articlepeer-review

    69 Scopus citations


    Postoperative ileus is a preventable disease with surprising economic consequences. Understanding the triad of dysmotility in conjunction with an enhanced recovery program improves patient outcome, decreases length of stay in hospital, and lowers the cost. Alvimopan and other investigational promotility medications can help attain these goals. Surgeons should avoid labeling all postoperative abdominal distention as ileus, which not only prevents timely diagnosis and treatment of early postoperative small bowel obstruction or acute colonic pseudo-obstruction but also increases patient morbidity and mortality.

    Original languageEnglish (US)
    Pages (from-to)259-272
    Number of pages14
    JournalSurgical Clinics of North America
    Issue number2
    StatePublished - Apr 1 2012


    • Abdominal surgery
    • Alvimopan
    • Early postoperative small bowel obstruction
    • Ogilvie syndrome
    • Postoperative ileus

    ASJC Scopus subject areas

    • Surgery


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