Pathological features of Trypanosoma cruzi infections of Rattus rattus

J. H. Edgcomb, D. H. Walker, C. M. Johnson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Naturally acquired T. cruzi infections were studied in R. rattus kept in the laboratory for intervals from one day to 33 months. T. cruzi was found at necropsy in the tissue of 85 (51%) of 167 rats kept three months or less, 7 (50%) of 14 rats kept 3 to 12 months, and 5 (24%) of 21 rats kept 12 to 33 months. Myocarditis and meningoencephalitis were the principal pathological lesions present. The pathological lesions of naturally acquired T. cruzi infections in R. rattus resemble the lesions of Chagas disease, as it is seen in Panamanians.

Original languageEnglish (US)
Pages (from-to)36-38
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Issue number1
StatePublished - 1973
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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