Pathology

Nithisha Thatikonda; Todd Masel

doi:10.1007/978-3-031-77741-7_10

Pathology

Nithisha Thatikonda, Todd Masel

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter provides a comprehensive overview of the pathology of various epilepsy syndromes, traversing through an array of structural etiologies such as mesial temporal sclerosis, cortical malformations, neoplasms, vascular anomalies, and neurocutaneous syndromes, among others. Key histopathological features are discussed, delving into molecular pathways contributing to epileptogenesis, imaging, and electrographic features wherever necessary. Additionally, the chapter emphasizes the importance of identifying the underlying structural pathology underpinning epileptogenesis, which is a crucial prerequisite for prompt diagnosis and the informed direction of management, particularly in cases amenable to surgical resection.

Original language	English (US)
Title of host publication	Epilepsy Fundamentals
Subtitle of host publication	A Concise Clinical Guide
Publisher	Springer Nature
Pages	127-141
Number of pages	15
ISBN (Electronic)	9783031777417
ISBN (Print)	9783031777400
DOIs	https://doi.org/10.1007/978-3-031-77741-7_10
State	Published - Jan 1 2005
Externally published	Yes

ASJC Scopus subject areas

General Medicine
General Neuroscience

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10.1007/978-3-031-77741-7_10

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title = "Pathology",

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AU - Masel, Todd

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AB - This chapter provides a comprehensive overview of the pathology of various epilepsy syndromes, traversing through an array of structural etiologies such as mesial temporal sclerosis, cortical malformations, neoplasms, vascular anomalies, and neurocutaneous syndromes, among others. Key histopathological features are discussed, delving into molecular pathways contributing to epileptogenesis, imaging, and electrographic features wherever necessary. Additionally, the chapter emphasizes the importance of identifying the underlying structural pathology underpinning epileptogenesis, which is a crucial prerequisite for prompt diagnosis and the informed direction of management, particularly in cases amenable to surgical resection.

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Pathology

Abstract

ASJC Scopus subject areas

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