Pathology of the pleura: What the pulmonologists need to know

Philip T. Cagle, Timothy Craig Allen

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Primary and metastatic pleural neoplasms, and nonneoplastic pleural diseases, can have similar clinical, radiographic and gross features. However, treatments and prognoses of these diverse pleural conditions vary greatly. Accurate diagnosis of pleural disease is therefore extremely important, and histological interpretation of pleural biopsies is vital to rendering an accurate diagnosis. Smaller biopsies contribute to the difficulties in accurately characterizing pleural lesions, and immunostains are frequently employed in their assessment. Diffuse malignant mesothelioma, the most common primary pulmonary neoplasm, is rare; however, other less common primary pleural neoplasms, including solitary fibrous tumour, the most common benign primary pleural neoplasm, occur. These neoplasms are discussed. Also, non-neoplastic pleural diseases, including granulomatous pleuritis, eosinophilic pleuritis and fibrous and fibrinous pleuritis, among other diseases, are discussed.

Original languageEnglish (US)
Pages (from-to)430-438
Number of pages9
JournalRespirology
Volume16
Issue number3
DOIs
StatePublished - Apr 1 2011

Keywords

  • Atypical mesothelial cell hyperplasia
  • Mesothelioma
  • Pleura
  • Pleuritis
  • Solitary fibrous tumour

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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