Pathophysiology of burns

Maike Keck, David H. Herndon, Lars P. Kamolz, Manfred Frey, Marc G. Jeschke

Research output: Contribution to journalReview articlepeer-review

87 Scopus citations

Abstract

Burn injury represents a significant problem worldwide. Advances in therapy strategies, based on better understanding of the pathophysiologic responses after burn injury have improved the clinical outcome of patients with burn injuries over the past years. This article describes the present understanding of the pathophysiology of a burn injury including both the local and systemic responses, focusing on the many facets of organ and systemic effects directly resulting from hypovolemia and circulating mediators following burn trauma.

Original languageEnglish (US)
Pages (from-to)327-336
Number of pages10
JournalWiener Medizinische Wochenschrift
Volume159
Issue number13-14
DOIs
StatePublished - Jul 2009

Keywords

  • Burn injury
  • Hemodynamics
  • Hypovolemia
  • Mediators
  • Pathophysiology

ASJC Scopus subject areas

  • General Medicine

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