Pattern analysis of drug-induced skin diseases

Hildamari Justiniano, Alma C. Berlingeri-Ramos, Jorge L. Sánchez

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Drug eruptions are common adverse reactions to drug therapy and are a frequent reason for consultation in clinical practice. Even though any medication can potentially cause an adverse cutaneous reaction, some drugs are implicated more commonly than others. Histologically, drugs can elicit a variety of inflammatory disease patterns in the skin and panniculus, no pattern being specific for a particular drug. The most common pattern elicited by systemically administered medications is the perivascular pattern. Psoriasiform or granulomatous patterns are rarely caused by medications. The usual histologic patterns of drug eruptions are discussed in this review using the basic patterns of inflammatory diseases. Clinicopathologic correlation is established for relevant patterns. However, the changes of drug-induced skin disease must be made considering clinical presentation, histopathological analysis, and course of the disease.

Original languageEnglish (US)
Pages (from-to)352-369
Number of pages18
JournalAmerican Journal of Dermatopathology
Volume30
Issue number4
DOIs
StatePublished - Aug 2008

Fingerprint

Skin Diseases
Drug Eruptions
Pharmaceutical Preparations
Skin
Referral and Consultation
Drug Therapy

Keywords

  • Drug eruptions
  • Histopathologic pattern

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology
  • Medicine(all)

Cite this

Justiniano, H., Berlingeri-Ramos, A. C., & Sánchez, J. L. (2008). Pattern analysis of drug-induced skin diseases. American Journal of Dermatopathology, 30(4), 352-369. https://doi.org/10.1097/DAD.0b013e3181722ef4

Pattern analysis of drug-induced skin diseases. / Justiniano, Hildamari; Berlingeri-Ramos, Alma C.; Sánchez, Jorge L.

In: American Journal of Dermatopathology, Vol. 30, No. 4, 08.2008, p. 352-369.

Research output: Contribution to journalArticle

Justiniano, H, Berlingeri-Ramos, AC & Sánchez, JL 2008, 'Pattern analysis of drug-induced skin diseases', American Journal of Dermatopathology, vol. 30, no. 4, pp. 352-369. https://doi.org/10.1097/DAD.0b013e3181722ef4
Justiniano, Hildamari ; Berlingeri-Ramos, Alma C. ; Sánchez, Jorge L. / Pattern analysis of drug-induced skin diseases. In: American Journal of Dermatopathology. 2008 ; Vol. 30, No. 4. pp. 352-369.
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