TY - JOUR
T1 - Pediatric Intracerebral Hemorrhage Management—Consensus Statement of the International Pediatric Stroke Organization—Part 1
T2 - Acute Phase and Workup
AU - Boulouis, Grégoire
AU - Fox, Christine K.
AU - Waak, Michaela
AU - Sporns, Peter B.
AU - Mailo, Janette A.
AU - Beslow, Lauren A.
AU - Wintermark, Max
AU - Chung, Melissa G.
AU - Harrar, Dana B.
AU - Vossough, Arastoo
AU - Hausman-Kedem, Moran
AU - Naggara, Olivier
AU - Jiang, Bin
AU - Requejo, Flavio
AU - Chaudhary, Neeraj
AU - Benichi, Sandro
AU - Radvany, Martin G.
AU - Martinez, Mesha
AU - Vadivelu, Sudhakar
AU - Kansagra, Akash P.
AU - Aagaard-Kienitz, Beverly
AU - Marti-Fàbregas, Joan
AU - Chikkannaiah, Mahesh
AU - Pasi, Marco
AU - Grossberg, Jonathan A.
AU - Chevignard, Mathilde
AU - Mrakotsky, Christine
AU - Fullerton, Heather J.
AU - Dlamini, Nomazulu
AU - Lehman, Laura L.
N1 - Publisher Copyright:
© 2025 The Author(s). Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. JAHA is available at: www.ahajournals.org/journal/jaha
PY - 2025/12/30
Y1 - 2025/12/30
N2 - Pediatric intracerebral hemorrhage (pICH) is a rare but serious neurologic emergency associated with significant morbidity. Although pICH accounts for nearly half of all pediatric strokes, it remains understudied, and dedicated evidencebased management guidelines are lacking. To address this gap, the International Pediatric Stroke Organization convened a multidisciplinary international working group in 2020 to develop a comprehensive, consensus-based framework for the acute evaluation and management of pICH in children aged 28 days to 18 years. The working group included child neurologists, neurointensivists, neurosurgeons, neuroradiologists, and neurointerventionalists. Subgroups conducted systematic literature reviews and formulated key clinical questions. A modified Delphi process was used to derive consensus statements across 6 domains: prehospital and emergency care, diagnostic imaging and workup, neurocritical care and medical management, neurosurgical and neurointerventional approaches, and identification of knowledge gaps. Through rounds of structured review and voting, 21 consensus statements were developed and approved. The process was endorsed by multiple professional societies. This represents the first international, multidisciplinary, multisociety consensus statement focused on the acute management of pICH in children. It provides structured, expert-driven guidance to inform clinical decision-making, reduce practice variability, and highlight areas for future research. These consensus statements aim to support clinicians worldwide in improving outcomes for children with pICH.
AB - Pediatric intracerebral hemorrhage (pICH) is a rare but serious neurologic emergency associated with significant morbidity. Although pICH accounts for nearly half of all pediatric strokes, it remains understudied, and dedicated evidencebased management guidelines are lacking. To address this gap, the International Pediatric Stroke Organization convened a multidisciplinary international working group in 2020 to develop a comprehensive, consensus-based framework for the acute evaluation and management of pICH in children aged 28 days to 18 years. The working group included child neurologists, neurointensivists, neurosurgeons, neuroradiologists, and neurointerventionalists. Subgroups conducted systematic literature reviews and formulated key clinical questions. A modified Delphi process was used to derive consensus statements across 6 domains: prehospital and emergency care, diagnostic imaging and workup, neurocritical care and medical management, neurosurgical and neurointerventional approaches, and identification of knowledge gaps. Through rounds of structured review and voting, 21 consensus statements were developed and approved. The process was endorsed by multiple professional societies. This represents the first international, multidisciplinary, multisociety consensus statement focused on the acute management of pICH in children. It provides structured, expert-driven guidance to inform clinical decision-making, reduce practice variability, and highlight areas for future research. These consensus statements aim to support clinicians worldwide in improving outcomes for children with pICH.
KW - nontraumatic cerebral hemorrhage
KW - pediatric hemorrhagic stroke
KW - pediatric intracerebral hemorrhage
UR - https://www.scopus.com/pages/publications/105028749718
UR - https://www.scopus.com/pages/publications/105028749718#tab=citedBy
U2 - 10.1161/JAHA.124.039594
DO - 10.1161/JAHA.124.039594
M3 - Article
C2 - 41467366
AN - SCOPUS:105028749718
SN - 2047-9980
VL - 15
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 1
M1 - e039594
ER -