Pentoxifylline and cyclosporine in the treatment of febrile ulceronecrotic Mucha-Habermann disease

Miranda A. Uzoma; Michael G. Wilkerson; Vicki L. Carr; Gail S. Westhoven; Sharon A.S. Raimer

doi:10.1111/j.1525-1470.2012.01862.x

Pentoxifylline and cyclosporine in the treatment of febrile ulceronecrotic Mucha-Habermann disease

Miranda A. Uzoma, Michael G. Wilkerson, Vicki L. Carr, Gail S. Westhoven, Sharon A.S. Raimer

Dermatology

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

We describe two pediatric cases of febrile ulceronecrotic Mucha-Habermann disease (FUMHD) with response to pentoxifylline and cyclosporine therapies. Based on our review of the literature, we are presenting the first case of FUMHD treated with pentoxifylline and the third case of FUMHD successfully treated with cyclosporine. These agents may be of therapeutic benefit in the treatment of FUMHD, in part by suppressing tumor necrosis factor-alpha, which we believe may mediate the disease process.

Original language	English (US)
Pages (from-to)	525-527
Number of pages	3
Journal	Pediatric Dermatology
Volume	31
Issue number	4
DOIs	https://doi.org/10.1111/j.1525-1470.2012.01862.x
State	Published - 2014

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Dermatology

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10.1111/j.1525-1470.2012.01862.x

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title = "Pentoxifylline and cyclosporine in the treatment of febrile ulceronecrotic Mucha-Habermann disease",

abstract = "We describe two pediatric cases of febrile ulceronecrotic Mucha-Habermann disease (FUMHD) with response to pentoxifylline and cyclosporine therapies. Based on our review of the literature, we are presenting the first case of FUMHD treated with pentoxifylline and the third case of FUMHD successfully treated with cyclosporine. These agents may be of therapeutic benefit in the treatment of FUMHD, in part by suppressing tumor necrosis factor-alpha, which we believe may mediate the disease process.",

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T1 - Pentoxifylline and cyclosporine in the treatment of febrile ulceronecrotic Mucha-Habermann disease

AU - Uzoma, Miranda A.

AU - Wilkerson, Michael G.

AU - Carr, Vicki L.

AU - Westhoven, Gail S.

AU - Raimer, Sharon A.S.

PY - 2014

Y1 - 2014

N2 - We describe two pediatric cases of febrile ulceronecrotic Mucha-Habermann disease (FUMHD) with response to pentoxifylline and cyclosporine therapies. Based on our review of the literature, we are presenting the first case of FUMHD treated with pentoxifylline and the third case of FUMHD successfully treated with cyclosporine. These agents may be of therapeutic benefit in the treatment of FUMHD, in part by suppressing tumor necrosis factor-alpha, which we believe may mediate the disease process.

AB - We describe two pediatric cases of febrile ulceronecrotic Mucha-Habermann disease (FUMHD) with response to pentoxifylline and cyclosporine therapies. Based on our review of the literature, we are presenting the first case of FUMHD treated with pentoxifylline and the third case of FUMHD successfully treated with cyclosporine. These agents may be of therapeutic benefit in the treatment of FUMHD, in part by suppressing tumor necrosis factor-alpha, which we believe may mediate the disease process.

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Pentoxifylline and cyclosporine in the treatment of febrile ulceronecrotic Mucha-Habermann disease

Abstract

ASJC Scopus subject areas

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