Perceptions of reimbursement for clinical trial participation

Carmen Radecki Breitkopf, Melissa Loza, Kathleen Vincent, Thomas Moench, Lawrence R. Stanberry, Susan L. Rosenthal

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A GREATER UNDERSTANDING OF participant views regarding reimbursement will help investigators plan studies that have better potential for reaching target enrollment, maximize efficient recruitment, maintain scientific integrity, and enhance retention over time. As part of a clinical trial in the area of sexual health, healthy women's perceptions of reimbursement for research participation were investigated. Semi-structured, audio-recorded, qualitative interviews were conducted immediately upon women's completion of the clinical trial to enable a participant-driven understanding of perceptions about monetary reimbursement. Audio-recordings were transcribed and analyzed using framework analysis. Women (N = 30) had a mean age of 29.5 ± 5.7 years (range 22-45 years). Sixty-three percent of participants (n = 19) were non-Hispanic (white n = 13, black n = 4, and Asian n = 2), while the remaining were Hispanic (n = 11). Seventy-three percent (n = 22) reported previous participation in research. In general, women viewed reimbursement as a benefit to research participation, the amount of which should reflect time, the inconvenience to the research subject, and the potential for unknown risks in the short-and long-term. They believed reimbursement should take into account the degree of risk of the study, with investigations of experimental products offering greater reimbursement. Women believed that monetary reimbursement is unlikely to coerce an individual to volunteer for a study involving procedures or requirements that they found unacceptable. The results of this study can be used to provide guidance to those planning and evaluating reimbursement for research participation.

Original languageEnglish (US)
Pages (from-to)31-38
Number of pages8
JournalJournal of Empirical Research on Human Research Ethics
Volume6
Issue number3
DOIs
StatePublished - Sep 2011
Externally publishedYes

Fingerprint

Clinical Trials
participation
Research
Audio recordings
Research Subjects
Reproductive Health
qualitative interview
Hispanic Americans
integrity
recording
Volunteers
Research Personnel
Interviews
Planning
planning
health
time

Keywords

  • Clinical trial
  • Coercion
  • Incentive
  • Qualitative interviews
  • Reimbursement
  • Reproductive health
  • Risk
  • Subject payment

ASJC Scopus subject areas

  • Education
  • Communication
  • Social Psychology
  • Law

Cite this

Perceptions of reimbursement for clinical trial participation. / Breitkopf, Carmen Radecki; Loza, Melissa; Vincent, Kathleen; Moench, Thomas; Stanberry, Lawrence R.; Rosenthal, Susan L.

In: Journal of Empirical Research on Human Research Ethics, Vol. 6, No. 3, 09.2011, p. 31-38.

Research output: Contribution to journalArticle

Breitkopf, Carmen Radecki ; Loza, Melissa ; Vincent, Kathleen ; Moench, Thomas ; Stanberry, Lawrence R. ; Rosenthal, Susan L. / Perceptions of reimbursement for clinical trial participation. In: Journal of Empirical Research on Human Research Ethics. 2011 ; Vol. 6, No. 3. pp. 31-38.
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