Performance of two commercial glycoprotein G-based enzyme immunoassays for detecting antibodies to herpes simplex viruses 1 and 2 in children and young adolescents

Charles T. Leach, Rhoda L. Ashley, Jacques Baillargeon, Hal B. Jenson

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

In 61 patients 1 to 14 years of age, the Gull/Meridian enzyme-linked immunosorbent assay (ELISA) had a sensitivity of 100% for herpes simplex virus type 1 (HSV-1) and specificities of 74% for HSV-1 and 48% for HSV-2. In 128 similarly aged patients, the HerpeSelect ELISA (Focus Technologies) showed sensitivities of 80% for HSV-1 and 88% for HSV-2, and specificities of 97% for HSV-1 and 100% for HSV-2.

Original languageEnglish (US)
Pages (from-to)1124-1125
Number of pages2
JournalClinical and Diagnostic Laboratory Immunology
Volume9
Issue number5
DOIs
StatePublished - Sep 2002
Externally publishedYes

Fingerprint

Human Herpesvirus 2
Human Herpesvirus 1
Immunoenzyme Techniques
Viruses
Glycoproteins
Immunosorbents
Antibodies
Enzymes
Assays
Enzyme-Linked Immunosorbent Assay
Charadriiformes
Meridians
Technology

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology and Allergy
  • Clinical Biochemistry
  • Immunology

Cite this

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abstract = "In 61 patients 1 to 14 years of age, the Gull/Meridian enzyme-linked immunosorbent assay (ELISA) had a sensitivity of 100{\%} for herpes simplex virus type 1 (HSV-1) and specificities of 74{\%} for HSV-1 and 48{\%} for HSV-2. In 128 similarly aged patients, the HerpeSelect ELISA (Focus Technologies) showed sensitivities of 80{\%} for HSV-1 and 88{\%} for HSV-2, and specificities of 97{\%} for HSV-1 and 100{\%} for HSV-2.",
author = "Leach, {Charles T.} and Ashley, {Rhoda L.} and Jacques Baillargeon and Jenson, {Hal B.}",
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T1 - Performance of two commercial glycoprotein G-based enzyme immunoassays for detecting antibodies to herpes simplex viruses 1 and 2 in children and young adolescents

AU - Leach, Charles T.

AU - Ashley, Rhoda L.

AU - Baillargeon, Jacques

AU - Jenson, Hal B.

PY - 2002/9

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AB - In 61 patients 1 to 14 years of age, the Gull/Meridian enzyme-linked immunosorbent assay (ELISA) had a sensitivity of 100% for herpes simplex virus type 1 (HSV-1) and specificities of 74% for HSV-1 and 48% for HSV-2. In 128 similarly aged patients, the HerpeSelect ELISA (Focus Technologies) showed sensitivities of 80% for HSV-1 and 88% for HSV-2, and specificities of 97% for HSV-1 and 100% for HSV-2.

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