Peripheral acid-sensing ion channels and P2X receptors contribute to mechanical allodynia in a rodent thrombus-induced ischemic pain model

Keyphrases

• Rodents 100%
• Pain Models 100%
• Mechanical Allodynia 100%
• Thrombus 100%
• P2X Receptors 100%
• Anion Receptor 100%
• Ischemic Pain 100%
• ASIC1a 100%
• Amiloride 57%
• PPADS 57%
• Channel Blocker 28%
• Ischemia 28%
• Transient Receptor Potential Vanilloid 1 (TRPV1) 28%
• Peripheral Arterial Disease 28%
• P2X Antagonists 28%
• AMG9810 28%
• Acidosis 14%
• Pathophysiology 14%
• Signaling Mechanism 14%
• Ca2+ 14%
• Mechanistic Information 14%
• Nociception 14%
• Beta-blockers 14%
• Peripheral Administration 14%
• Femoral Artery 14%
• ATP Release 14%
• Protein Kinase C Inhibitor 14%
• Chelerythrine 14%
• Therapeutic Management 14%
• Iron(III) Chloride 14%
• Protein Kinase C Signaling 14%
• Calcium Chelator 14%
• Channel Antagonist 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Thrombus 100%
• Purinergic P2X Receptor 100%
• Mechanical Allodynia 100%
• Acid Sensing Ion Channel 100%
• Amiloride 66%
• PPADS 66%
• Ischemia 33%
• Acid Sensing Ion Channel Blocking Agent 33%
• Peripheral Occlusive Artery Disease 33%
• Vanilloid Receptor 1 33%
• Pathophysiology 16%
• Calcium Ion 16%
• Adenosine Triphosphate 16%
• Protein Kinase C 16%
• Egtazic Acid 16%
• Protein Kinase C Inhibitor 16%
• Chelerythrine 16%
• Calcium Chelating Agent 16%
• Vanilloid Receptor 1 Antagonist 16%

Neuroscience

• Allodynia 100%
• Thrombus 100%
• Purinergic P2X Receptor 100%
• Acid-Sensing Ion Channel 100%
• PPADS 57%
• Amiloride 57%
• Vanilloid Receptor 1 42%
• Protein Kinase C 28%
• Ion Channel Blockers 28%
• Ischemia 28%
• Nociception 14%
• Adenosine Triphosphate 14%
• Signaling Mechanism 14%
• Chelating Agent 14%
• Chelerythrine 14%