Permeable tubes increase the length of the gap that regenerating axons can span

Chung Bii Jenq; Richard E. Coggeshall

doi:10.1016/0006-8993(87)90379-9

Permeable tubes increase the length of the gap that regenerating axons can span

Chung Bii Jenq, Richard E. Coggeshall

Neuroscience & Cell

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

After placement of stumps of transected rat sciatic nerve in an impermeable tube, the maximum gap the axons can span is 10 mm. The present study shows that the regenerating axons cross much longer gaps if the tube is made permeable. This improvement does not require another nerve as a transplant nor the preplacement of extracellular materials in the tube. Possible mechanisms for this improvement are discussed.

Original language	English (US)
Pages (from-to)	239-242
Number of pages	4
Journal	Brain Research
Volume	408
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(87)90379-9
State	Published - Apr 7 1987

Keywords

Axonal regeneration
Nerve transection
Permeable tube

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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