Permeable tubes increase the length of the gap that regenerating axons can span

Chung Bii Jenq, Richard E. Coggeshall

Research output: Contribution to journalArticle

87 Scopus citations

Abstract

After placement of stumps of transected rat sciatic nerve in an impermeable tube, the maximum gap the axons can span is 10 mm. The present study shows that the regenerating axons cross much longer gaps if the tube is made permeable. This improvement does not require another nerve as a transplant nor the preplacement of extracellular materials in the tube. Possible mechanisms for this improvement are discussed.

Original languageEnglish (US)
Pages (from-to)239-242
Number of pages4
JournalBrain Research
Volume408
Issue number1-2
DOIs
StatePublished - Apr 7 1987

Keywords

  • Axonal regeneration
  • Nerve transection
  • Permeable tube

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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