Abstract
After placement of stumps of transected rat sciatic nerve in an impermeable tube, the maximum gap the axons can span is 10 mm. The present study shows that the regenerating axons cross much longer gaps if the tube is made permeable. This improvement does not require another nerve as a transplant nor the preplacement of extracellular materials in the tube. Possible mechanisms for this improvement are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 239-242 |
| Number of pages | 4 |
| Journal | Brain Research |
| Volume | 408 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Apr 7 1987 |
| Externally published | Yes |
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Keywords
- Axonal regeneration
- Nerve transection
- Permeable tube
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)
Cite this
Permeable tubes increase the length of the gap that regenerating axons can span. / Jenq, Chung Bii; Coggeshall, Richard E.
In: Brain Research, Vol. 408, No. 1-2, 07.04.1987, p. 239-242.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Permeable tubes increase the length of the gap that regenerating axons can span
AU - Jenq, Chung Bii
AU - Coggeshall, Richard E.
PY - 1987/4/7
Y1 - 1987/4/7
N2 - After placement of stumps of transected rat sciatic nerve in an impermeable tube, the maximum gap the axons can span is 10 mm. The present study shows that the regenerating axons cross much longer gaps if the tube is made permeable. This improvement does not require another nerve as a transplant nor the preplacement of extracellular materials in the tube. Possible mechanisms for this improvement are discussed.
AB - After placement of stumps of transected rat sciatic nerve in an impermeable tube, the maximum gap the axons can span is 10 mm. The present study shows that the regenerating axons cross much longer gaps if the tube is made permeable. This improvement does not require another nerve as a transplant nor the preplacement of extracellular materials in the tube. Possible mechanisms for this improvement are discussed.
KW - Axonal regeneration
KW - Nerve transection
KW - Permeable tube
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U2 - 10.1016/0006-8993(87)90379-9
DO - 10.1016/0006-8993(87)90379-9
M3 - Article
VL - 408
SP - 239
EP - 242
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1-2
ER -