Persistence of H7N9 virus antibody response 2 years after infection

Lin Yao, Guo Lin Wang, Li Ling Chen, Cheng Liu, Li Jun Duan, Gregory C. Gray, Mai Juan Ma

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


We measured antibodies against H7N9 virus 2 years after infection in 14 patients who were infected during October 2016-September 2017. Approximately 2 years after infection, antibody titers ≥10 were detectable in 13 (92.9%) patients. Three (21.4%) of 14 patients had hemagglutination inhibition titers ≥40, and their geometric mean titer (GMT) was 20 (95% CI 15.7-28.1), whereas 10 (71.4%) and all 14 (100%) of the 14 patients had titers ≥40, and GMTs at 34.4 (95% CI 25.7-51.2) and 73.45 (54.7-106.7) for neuraminidase inhibition and microneutralization antibodies, respectively. Our findings suggest that H7N9 infection may induce long-term antibody response at least 2 years after infection.

Original languageEnglish (US)
Pages (from-to)210-214
Number of pages5
JournalInfluenza and other respiratory viruses
Issue number2
StatePublished - Mar 1 2020
Externally publishedYes


  • H7N9 viruses
  • antibody response
  • influenza A virus
  • persistence
  • serological

ASJC Scopus subject areas

  • Epidemiology
  • Pulmonary and Respiratory Medicine
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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