Persistence of Rickettsia prowazekii in cotton rat macrophage cultures.

N. G. Kekcheeva, I. N. Kokorin, Vsevolod Popov, E. A. Chereshkova, N. S. Smirnova, O. A. Vovk, E. M. Shirokova

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Rickettsia prowazekii is able to multiply and persist for a long time in cotton rat macrophage culture (29-days observation period). Electron microscopic studies showed that the structure of Rickettsiae remained intact at different intervals post-inoculation (p.i.). In the course of persistence Rickettsiae revealed a reduced capacity to infect chick embryos and guinea pigs, however, the infectious agent could be isolated at all stages of persistence of cultured cells such as fibroblasts of the guinea pig embryo, macrophages of intact cotton rats.

Original languageEnglish (US)
Pages (from-to)103-110
Number of pages8
JournalActa Virologica
Volume36
Issue number1
StatePublished - Jan 1992
Externally publishedYes

Fingerprint

Rickettsia prowazekii
Sigmodontinae
Rickettsia
Guinea Pigs
Macrophages
Chick Embryo
Cultured Cells
Embryonic Structures
Fibroblasts
Observation
Electrons

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Kekcheeva, N. G., Kokorin, I. N., Popov, V., Chereshkova, E. A., Smirnova, N. S., Vovk, O. A., & Shirokova, E. M. (1992). Persistence of Rickettsia prowazekii in cotton rat macrophage cultures. Acta Virologica, 36(1), 103-110.

Persistence of Rickettsia prowazekii in cotton rat macrophage cultures. / Kekcheeva, N. G.; Kokorin, I. N.; Popov, Vsevolod; Chereshkova, E. A.; Smirnova, N. S.; Vovk, O. A.; Shirokova, E. M.

In: Acta Virologica, Vol. 36, No. 1, 01.1992, p. 103-110.

Research output: Contribution to journalArticle

Kekcheeva, NG, Kokorin, IN, Popov, V, Chereshkova, EA, Smirnova, NS, Vovk, OA & Shirokova, EM 1992, 'Persistence of Rickettsia prowazekii in cotton rat macrophage cultures.', Acta Virologica, vol. 36, no. 1, pp. 103-110.
Kekcheeva NG, Kokorin IN, Popov V, Chereshkova EA, Smirnova NS, Vovk OA et al. Persistence of Rickettsia prowazekii in cotton rat macrophage cultures. Acta Virologica. 1992 Jan;36(1):103-110.
Kekcheeva, N. G. ; Kokorin, I. N. ; Popov, Vsevolod ; Chereshkova, E. A. ; Smirnova, N. S. ; Vovk, O. A. ; Shirokova, E. M. / Persistence of Rickettsia prowazekii in cotton rat macrophage cultures. In: Acta Virologica. 1992 ; Vol. 36, No. 1. pp. 103-110.
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