Persistent pulmonary hypertension of the newborn: Not a honeymoon anymore

M. Terese Verklan

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Persistent pulmonary hypertension of the newborn is a disorder of transition to extrauterine life, in which the newly born baby cannot decrease the high pulmonary vascular resistance and low pulmonary blood flow, characteristic of the fetus, to that of a low pulmonary vascular resistance and high pulmonary blood flow necessary for postnatal survival. The syndrome primarily affects the neonate 34 weeks postmenstrual age and greater. The article will summarize the latest understanding of the pathophysiology and review innovations in management strategies that have greatly decreased mortality and morbidity since the advent of neonatal intensive care units.

Original languageEnglish (US)
Pages (from-to)108-112
Number of pages5
JournalJournal of Perinatal and Neonatal Nursing
Issue number1
StatePublished - 2006
Externally publishedYes


  • High-frequency ventilation
  • Inhaled nitric oxide
  • PPHN
  • Pathophysiology

ASJC Scopus subject areas

  • Pediatrics
  • Critical Care
  • Maternity and Midwifery


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