Personalized treatment of breast cancer

Masakazu Toi, Eric Winer, John R. Benson, Vicki Klimberg

Research output: Book/ReportBook

Abstract

This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.

Original languageEnglish (US)
PublisherSpringer Japan
Number of pages321
ISBN (Electronic)9784431555520
ISBN (Print)9784431555513
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

Breast Neoplasms
Therapeutics
Lymph Nodes
Nomograms
Translational Medical Research
Neoplasms
Research Design
Radiotherapy
Research Personnel
Neoplasm Metastasis
Physicians
Mutation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Personalized treatment of breast cancer. / Toi, Masakazu; Winer, Eric; Benson, John R.; Klimberg, Vicki.

Springer Japan, 2016. 321 p.

Research output: Book/ReportBook

Toi, Masakazu ; Winer, Eric ; Benson, John R. ; Klimberg, Vicki. / Personalized treatment of breast cancer. Springer Japan, 2016. 321 p.
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