Abstract
Pharmacognostic, phytochemical and acute toxicity studies of Cassia fistula leaves were performed which led to the isolation of a steroidal compound (β-sitosterol) and reported for the first time from this plant. The structure of the compound established on the basis of extensive spectroscopic analysis including UV spectra, IR spectra, 1H- NMR spectra, Mass spectral data. All the pharmacognostic experimental evidences conclusively prove the identity and quality of the leaves of Cassia fistula Linn. The acute toxicity of different extracts on animal models has also been studied to access the minimum lethal dose (MLD). All the spectroscopic data were compared with the β-sitosterol and found matched.
Original language | English (US) |
---|---|
Article number | 36 |
Pages (from-to) | 210-214 |
Number of pages | 5 |
Journal | International Journal of Pharmaceutical Sciences Review and Research |
Volume | 25 |
Issue number | 1 |
State | Published - 2014 |
Externally published | Yes |
Keywords
- Acute-toxicity study
- Cassia fistula leaves
- Pharmacognostic parameters
- Phytochemical investigation
- β-sitosterol
ASJC Scopus subject areas
- Pharmaceutical Science