Pharmacotherapeutic Management of Nicotine Dependence in Pregnancy

Shannon M. Clark, Ramzy Nakad

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Smoking in pregnancy can cause serious adverse antenatal and postnatal morbidities, and a significant number of women continue to smoke in pregnancy despite these consequences. Early intervention in the form counseling from their physicians, pregnancy-specific self-help materials, counseling sessions with a health educator, and/or continued follow-up can result in better pregnancy outcomes and possibly long-term cessation. If a woman cannot quit despite these measures, pharmacotherapy can be considered. Currently, nicotine replacement therapy (NRT), transdermal patches, and bupropion are used in pregnancy, but data on the safety and efficacy are largely lacking.

Original languageEnglish (US)
Pages (from-to)297-311
Number of pages15
JournalObstetrics and gynecology clinics of North America
Issue number2
StatePublished - Jun 2011
Externally publishedYes


  • Management
  • Nicotine dependence
  • Pregnancy
  • Smoking

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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