Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit

A. J. Ricco; M. Parra; M. Piccini; D. Ly; D. Niesel; M. McGinnis; A. Kudlicki; J. W. Hines; L. Timucin; C. Beasley; R. Ricks; M. McIntyre; C. Friedericks; M. Henschke; R. Leung; M. Diaz-Aguado; C. Kitts; I. Mas; R. Rasay; E. Agasid; E. Luzzi; K. Ronzano; D. Squires; B. Yost

doi:10.31438/trf.hh2010.31

Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit

A. J. Ricco, M. Parra, M. Piccini, D. Ly, D. Niesel, M. McGinnis, A. Kudlicki, J. W. Hines, L. Timucin, C. Beasley, R. Ricks, M. McIntyre, C. Friedericks, M. Henschke, R. Leung, M. Diaz-Aguado, C. Kitts, I. Mas, R. Rasay, E. AgasidE. Luzzi, K. Ronzano, D. Squires, B. Yost

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

16 Scopus citations

Abstract

We designed, built, tested, space-qualified, launched, and downlinked bioanalytical data from PharmaSat, the first fully autonomous outer-space pharmaceutical dose-response bioanalytical system on a free-flying satellite. PharmaSat tracks microorganism culture population density and metabolic activity in 48 microw-ells via 3-color optical absorbance. Its 5.1-kg total mass includes solar cells, integrated spacecraft “bus” module (power/batteries/ control/communications), and a sealed containment vessel housing the biofluidic, optical, thermal, and sensor subsystems. Data were obtained from all subsystems over several days following nutrient introduction to initiate growth of Saccharomyces cerevisiae, followed by challenges with three dose levels of an antifungal agent.

Original language	English (US)
Title of host publication	2010 Solid-State Sensors, Actuators, and Microsystems Workshop
Editors	David J. Monk, Kimberly L. Turner
Publisher	Transducer Research Foundation
Pages	110-113
Number of pages	4
ISBN (Electronic)	0964002485, 9780964002487
DOIs	https://doi.org/10.31438/trf.hh2010.31
State	Published - 2010
Event	2010 Solid-State Sensors, Actuators, and Microsystems Workshop - Hilton Head Island, United States Duration: Jun 6 2010 → Jun 10 2010

Publication series

Name	Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop

Conference

Conference	2010 Solid-State Sensors, Actuators, and Microsystems Workshop
Country/Territory	United States
City	Hilton Head Island
Period	6/6/10 → 6/10/10

ASJC Scopus subject areas

Control and Systems Engineering
Electrical and Electronic Engineering
Hardware and Architecture

Access to Document

10.31438/trf.hh2010.31

Cite this

Ricco, A. J., Parra, M., Piccini, M., Ly, D., Niesel, D., McGinnis, M., Kudlicki, A., Hines, J. W., Timucin, L., Beasley, C., Ricks, R., McIntyre, M., Friedericks, C., Henschke, M., Leung, R., Diaz-Aguado, M., Kitts, C., Mas, I., Rasay, R., ... Yost, B. (2010). Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit. In D. J. Monk, & K. L. Turner (Eds.), 2010 Solid-State Sensors, Actuators, and Microsystems Workshop (pp. 110-113). (Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop). Transducer Research Foundation. https://doi.org/10.31438/trf.hh2010.31

Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit. / Ricco, A. J.; Parra, M.; Piccini, M. et al.
2010 Solid-State Sensors, Actuators, and Microsystems Workshop. ed. / David J. Monk; Kimberly L. Turner. Transducer Research Foundation, 2010. p. 110-113 (Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ricco, AJ, Parra, M, Piccini, M, Ly, D, Niesel, D, McGinnis, M, Kudlicki, A, Hines, JW, Timucin, L, Beasley, C, Ricks, R, McIntyre, M, Friedericks, C, Henschke, M, Leung, R, Diaz-Aguado, M, Kitts, C, Mas, I, Rasay, R, Agasid, E, Luzzi, E, Ronzano, K, Squires, D & Yost, B 2010, Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit. in DJ Monk & KL Turner (eds), 2010 Solid-State Sensors, Actuators, and Microsystems Workshop. Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop, Transducer Research Foundation, pp. 110-113, 2010 Solid-State Sensors, Actuators, and Microsystems Workshop, Hilton Head Island, United States, 6/6/10. https://doi.org/10.31438/trf.hh2010.31

Ricco AJ, Parra M, Piccini M, Ly D, Niesel D, McGinnis M et al. Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit. In Monk DJ, Turner KL, editors, 2010 Solid-State Sensors, Actuators, and Microsystems Workshop. Transducer Research Foundation. 2010. p. 110-113. (Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop). doi: 10.31438/trf.hh2010.31

Ricco, A. J. ; Parra, M. ; Piccini, M. et al. / Pharmasat : Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit. 2010 Solid-State Sensors, Actuators, and Microsystems Workshop. editor / David J. Monk ; Kimberly L. Turner. Transducer Research Foundation, 2010. pp. 110-113 (Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop).

@inproceedings{4dcc07542ee545b48deb7fe8fbb50430,

title = "Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit",

abstract = "We designed, built, tested, space-qualified, launched, and downlinked bioanalytical data from PharmaSat, the first fully autonomous outer-space pharmaceutical dose-response bioanalytical system on a free-flying satellite. PharmaSat tracks microorganism culture population density and metabolic activity in 48 microw-ells via 3-color optical absorbance. Its 5.1-kg total mass includes solar cells, integrated spacecraft “bus” module (power/batteries/ control/communications), and a sealed containment vessel housing the biofluidic, optical, thermal, and sensor subsystems. Data were obtained from all subsystems over several days following nutrient introduction to initiate growth of Saccharomyces cerevisiae, followed by challenges with three dose levels of an antifungal agent.",

author = "Ricco, \{A. J.\} and M. Parra and M. Piccini and D. Ly and D. Niesel and M. McGinnis and A. Kudlicki and Hines, \{J. W.\} and L. Timucin and C. Beasley and R. Ricks and M. McIntyre and C. Friedericks and M. Henschke and R. Leung and M. Diaz-Aguado and C. Kitts and I. Mas and R. Rasay and E. Agasid and E. Luzzi and K. Ronzano and D. Squires and B. Yost",

note = "Publisher Copyright: {\textcopyright} 2010TRF.; 2010 Solid-State Sensors, Actuators, and Microsystems Workshop ; Conference date: 06-06-2010 Through 10-06-2010",

year = "2010",

doi = "10.31438/trf.hh2010.31",

language = "English (US)",

series = "Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop",

publisher = "Transducer Research Foundation",

pages = "110--113",

editor = "Monk, \{David J.\} and Turner, \{Kimberly L.\}",

booktitle = "2010 Solid-State Sensors, Actuators, and Microsystems Workshop",

}

TY - GEN

T1 - Pharmasat

T2 - 2010 Solid-State Sensors, Actuators, and Microsystems Workshop

AU - Ricco, A. J.

AU - Parra, M.

AU - Piccini, M.

AU - Ly, D.

AU - Niesel, D.

AU - McGinnis, M.

AU - Kudlicki, A.

AU - Hines, J. W.

AU - Timucin, L.

AU - Beasley, C.

AU - Ricks, R.

AU - McIntyre, M.

AU - Friedericks, C.

AU - Henschke, M.

AU - Leung, R.

AU - Diaz-Aguado, M.

AU - Kitts, C.

AU - Mas, I.

AU - Rasay, R.

AU - Agasid, E.

AU - Luzzi, E.

AU - Ronzano, K.

AU - Squires, D.

AU - Yost, B.

PY - 2010

Y1 - 2010

N2 - We designed, built, tested, space-qualified, launched, and downlinked bioanalytical data from PharmaSat, the first fully autonomous outer-space pharmaceutical dose-response bioanalytical system on a free-flying satellite. PharmaSat tracks microorganism culture population density and metabolic activity in 48 microw-ells via 3-color optical absorbance. Its 5.1-kg total mass includes solar cells, integrated spacecraft “bus” module (power/batteries/ control/communications), and a sealed containment vessel housing the biofluidic, optical, thermal, and sensor subsystems. Data were obtained from all subsystems over several days following nutrient introduction to initiate growth of Saccharomyces cerevisiae, followed by challenges with three dose levels of an antifungal agent.

AB - We designed, built, tested, space-qualified, launched, and downlinked bioanalytical data from PharmaSat, the first fully autonomous outer-space pharmaceutical dose-response bioanalytical system on a free-flying satellite. PharmaSat tracks microorganism culture population density and metabolic activity in 48 microw-ells via 3-color optical absorbance. Its 5.1-kg total mass includes solar cells, integrated spacecraft “bus” module (power/batteries/ control/communications), and a sealed containment vessel housing the biofluidic, optical, thermal, and sensor subsystems. Data were obtained from all subsystems over several days following nutrient introduction to initiate growth of Saccharomyces cerevisiae, followed by challenges with three dose levels of an antifungal agent.

UR - https://www.scopus.com/pages/publications/84866518533

UR - https://www.scopus.com/inward/citedby.url?scp=84866518533&partnerID=8YFLogxK

U2 - 10.31438/trf.hh2010.31

DO - 10.31438/trf.hh2010.31

M3 - Conference contribution

AN - SCOPUS:84866518533

T3 - Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop

SP - 110

EP - 113

BT - 2010 Solid-State Sensors, Actuators, and Microsystems Workshop

A2 - Monk, David J.

A2 - Turner, Kimberly L.

PB - Transducer Research Foundation

Y2 - 6 June 2010 through 10 June 2010

ER -

Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit

Abstract

Publication series

Conference

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this