Abstract
The PhoP/PhoQ two-component system controls the extracellular magnesium depletion response in Salmonella enterica. Previous studies have shown that PhoP is unable to up-regulate its target genes in the absence of PhoQ function. In this work, we demonstrate that PhoP overexpression can substitute for PhoQ- and phosphorylation-dependent activation. Either a high concentration of PhoP or activation via phosphorylation stimulates PhoP self-association.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2476-2480 |
| Number of pages | 5 |
| Journal | Journal of bacteriology |
| Volume | 186 |
| Issue number | 8 |
| DOIs | |
| State | Published - Apr 2004 |
| Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
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