Phototherapy and Plasma Immunoreactive Prostaglandin A Values: Its Effect in Premature Infants

Charles E. Aplin, Ben H. Brouhard, Robert J. Cunningham, C. Joan Richardson

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Plasma immunoreactive prostaglandin A (iPGA) values were determined for 14 premature infants before and after 48 hours of phototherapy and in a control group of six age-matched premature infants. At 4 to 8 days of life, the infants who had received phototherapy for 48 hours had significantly lower iPGA values compared with controls. At 2 to 3 days of life, four infants with a clinically apparent patent ductus arteriosus were found to have significantly elevated iPGA values compared with controls. After 48 hours of phototherapy, these infants likewise had a significant decrease in iPGA values compared with controls; in all four infants, the ductus closed spontaneously. Phototherapy is an effective method for decreasing plasma iPGA values in premature infants. (Am J Dis Child 133:625-627, 1979.

Original languageEnglish (US)
Pages (from-to)625-627
Number of pages3
JournalAmerican Journal of Diseases of Children
Volume133
Issue number6
DOIs
StatePublished - Jun 1979

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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