Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Comfort O. Aiki-Raji, Patricia V. Aguilar, Yong Kuk Kwon, Sue Goetz, David L. Suarez, Aashish I. Jethra, Oyekanmi Nash, Christopher A.O. Adeyefa, Festus D. Adu, David Swayne, Christopher F. Basler

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

Original languageEnglish (US)
Pages (from-to)1753-1755
Number of pages3
JournalEmerging infectious diseases
Issue number11
StatePublished - Nov 2008
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases


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