Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Comfort O. Aiki-Raji, Patricia Aguilar, Yong Kuk Kwon, Sue Goetz, David L. Suarez, Aashish I. Jethra, Oyekanmi Nash, Christopher A O Adeyefa, Festus D. Adu, David Swayne, Christopher F. Basler

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

Original languageEnglish (US)
Pages (from-to)1753-1755
Number of pages3
JournalEmerging Infectious Diseases
Volume14
Issue number11
DOIs
StatePublished - Nov 2008
Externally publishedYes

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Influenza in Birds
Nigeria
Orthomyxoviridae
Chickens
Newcastle disease virus
Tropism
Virulence
Endothelial Cells

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

Cite this

Aiki-Raji, C. O., Aguilar, P., Kwon, Y. K., Goetz, S., Suarez, D. L., Jethra, A. I., ... Basler, C. F. (2008). Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria. Emerging Infectious Diseases, 14(11), 1753-1755. https://doi.org/10.3201/eid1411.080557

Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria. / Aiki-Raji, Comfort O.; Aguilar, Patricia; Kwon, Yong Kuk; Goetz, Sue; Suarez, David L.; Jethra, Aashish I.; Nash, Oyekanmi; Adeyefa, Christopher A O; Adu, Festus D.; Swayne, David; Basler, Christopher F.

In: Emerging Infectious Diseases, Vol. 14, No. 11, 11.2008, p. 1753-1755.

Research output: Contribution to journalArticle

Aiki-Raji, CO, Aguilar, P, Kwon, YK, Goetz, S, Suarez, DL, Jethra, AI, Nash, O, Adeyefa, CAO, Adu, FD, Swayne, D & Basler, CF 2008, 'Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria', Emerging Infectious Diseases, vol. 14, no. 11, pp. 1753-1755. https://doi.org/10.3201/eid1411.080557
Aiki-Raji, Comfort O. ; Aguilar, Patricia ; Kwon, Yong Kuk ; Goetz, Sue ; Suarez, David L. ; Jethra, Aashish I. ; Nash, Oyekanmi ; Adeyefa, Christopher A O ; Adu, Festus D. ; Swayne, David ; Basler, Christopher F. / Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria. In: Emerging Infectious Diseases. 2008 ; Vol. 14, No. 11. pp. 1753-1755.
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