Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Comfort O. Aiki-Raji, Patricia V. Aguilar, Yong Kuk Kwon, Sue Goetz, David L. Suarez, Aashish I. Jethra, Oyekanmi Nash, Christopher A.O. Adeyefa, Festus D. Adu, David Swayne, Christopher F. Basler

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

Original languageEnglish (US)
Pages (from-to)1753-1755
Number of pages3
JournalEmerging infectious diseases
Volume14
Issue number11
DOIs
StatePublished - Nov 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria'. Together they form a unique fingerprint.

  • Cite this

    Aiki-Raji, C. O., Aguilar, P. V., Kwon, Y. K., Goetz, S., Suarez, D. L., Jethra, A. I., Nash, O., Adeyefa, C. A. O., Adu, F. D., Swayne, D., & Basler, C. F. (2008). Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria. Emerging infectious diseases, 14(11), 1753-1755. https://doi.org/10.3201/eid1411.080557