Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Comfort O. Aiki-Raji; Patricia V. Aguilar; Yong Kuk Kwon; Sue Goetz; David L. Suarez; Aashish I. Jethra; Oyekanmi Nash; Christopher A.O. Adeyefa; Festus D. Adu; David Swayne; Christopher F. Basler

doi:10.3201/eid1411.080557

Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Comfort O. Aiki-Raji
, Patricia V. Aguilar
, Yong Kuk Kwon
, Sue Goetz
, David L. Suarez
, Aashish I. Jethra
, Oyekanmi Nash
, Christopher A.O. Adeyefa
, Festus D. Adu
, David Swayne
, Christopher F. Basler

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

Original language	English (US)
Pages (from-to)	1753-1755
Number of pages	3
Journal	Emerging infectious diseases
Volume	14
Issue number	11
DOIs	https://doi.org/10.3201/eid1411.080557
State	Published - Nov 2008
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.3201/eid1411.080557

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title = "Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria",

abstract = "Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.",

author = "Aiki-Raji, \{Comfort O.\} and Aguilar, \{Patricia V.\} and Kwon, \{Yong Kuk\} and Sue Goetz and Suarez, \{David L.\} and Jethra, \{Aashish I.\} and Oyekanmi Nash and Adeyefa, \{Christopher A.O.\} and Adu, \{Festus D.\} and David Swayne and Basler, \{Christopher F.\}",

year = "2008",

month = nov,

doi = "10.3201/eid1411.080557",

language = "English (US)",

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T1 - Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

AU - Aiki-Raji, Comfort O.

AU - Aguilar, Patricia V.

AU - Kwon, Yong Kuk

AU - Goetz, Sue

AU - Suarez, David L.

AU - Jethra, Aashish I.

AU - Nash, Oyekanmi

AU - Adeyefa, Christopher A.O.

AU - Adu, Festus D.

AU - Swayne, David

AU - Basler, Christopher F.

PY - 2008/11

Y1 - 2008/11

N2 - Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

AB - Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

UR - https://www.scopus.com/pages/publications/55549121960

UR - https://www.scopus.com/pages/publications/55549121960#tab=citedBy

U2 - 10.3201/eid1411.080557

DO - 10.3201/eid1411.080557

M3 - Article

C2 - 18976562

AN - SCOPUS:55549121960

SN - 1080-6040

VL - 14

SP - 1753

EP - 1755

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 11

ER -

Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Abstract

ASJC Scopus subject areas

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