Physiology of the vasopressin receptors

Marc O. Maybauer, Dirk M. Maybauer, Perenlei Enkhbaatar, Daniel L. Traber

Research output: Contribution to journalReview article

60 Scopus citations

Abstract

This review article summarizes the structure, signalling pathways, and tissue distribution of the vasopressin receptors, V1 vascular, V2 renal, V3 pituitary, and oxytocin receptors, as well as the P2 class of purinoceptors. The physiological effects of vasopressin on its receptors are described. The future direction with regard to the role of the V1a receptor in circulatory shock states is discussed; further studies with V1a receptor agonists are warranted to further develop treatment strategies to reduce mortality in life threatening diseases like septic shock.

Original languageEnglish (US)
Pages (from-to)253-263
Number of pages11
JournalBest Practice and Research: Clinical Anaesthesiology
Volume22
Issue number2
DOIs
StatePublished - Jun 1 2008

Keywords

  • V1 receptor agonist
  • amino acid sequences
  • arginine-vasopressin (AVP)
  • hypovolemia
  • oxytocin (ot)
  • sepsis
  • vasopressin
  • vasopressin (VP)

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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