Physiology of the vasopressin receptors

Marc O. Maybauer, Dirk M. Maybauer, Perenlei Enkhbaatar, Daniel L. Traber

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

This review article summarizes the structure, signalling pathways, and tissue distribution of the vasopressin receptors, V1 vascular, V2 renal, V3 pituitary, and oxytocin receptors, as well as the P2 class of purinoceptors. The physiological effects of vasopressin on its receptors are described. The future direction with regard to the role of the V1a receptor in circulatory shock states is discussed; further studies with V1a receptor agonists are warranted to further develop treatment strategies to reduce mortality in life threatening diseases like septic shock.

Original languageEnglish (US)
Pages (from-to)253-263
Number of pages11
JournalBest Practice and Research: Clinical Anaesthesiology
Volume22
Issue number2
DOIs
StatePublished - Jun 2008

Fingerprint

Oxytocin Receptors
Purinergic P2 Receptors
Vasopressin Receptors
Tissue Distribution
Septic Shock
Vasopressins
Blood Vessels
Shock
Kidney
Mortality
Direction compound

Keywords

  • amino acid sequences
  • arginine-vasopressin (AVP)
  • hypovolemia
  • oxytocin (ot)
  • sepsis
  • V1 receptor agonist
  • vasopressin
  • vasopressin (VP)

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Psychology(all)

Cite this

Physiology of the vasopressin receptors. / Maybauer, Marc O.; Maybauer, Dirk M.; Enkhbaatar, Perenlei; Traber, Daniel L.

In: Best Practice and Research: Clinical Anaesthesiology, Vol. 22, No. 2, 06.2008, p. 253-263.

Research output: Contribution to journalArticle

Maybauer, Marc O. ; Maybauer, Dirk M. ; Enkhbaatar, Perenlei ; Traber, Daniel L. / Physiology of the vasopressin receptors. In: Best Practice and Research: Clinical Anaesthesiology. 2008 ; Vol. 22, No. 2. pp. 253-263.
@article{d73f89e017be44e58c69b3a7e945d44b,
title = "Physiology of the vasopressin receptors",
abstract = "This review article summarizes the structure, signalling pathways, and tissue distribution of the vasopressin receptors, V1 vascular, V2 renal, V3 pituitary, and oxytocin receptors, as well as the P2 class of purinoceptors. The physiological effects of vasopressin on its receptors are described. The future direction with regard to the role of the V1a receptor in circulatory shock states is discussed; further studies with V1a receptor agonists are warranted to further develop treatment strategies to reduce mortality in life threatening diseases like septic shock.",
keywords = "amino acid sequences, arginine-vasopressin (AVP), hypovolemia, oxytocin (ot), sepsis, V1 receptor agonist, vasopressin, vasopressin (VP)",
author = "Maybauer, {Marc O.} and Maybauer, {Dirk M.} and Perenlei Enkhbaatar and Traber, {Daniel L.}",
year = "2008",
month = "6",
doi = "10.1016/j.bpa.2008.03.003",
language = "English (US)",
volume = "22",
pages = "253--263",
journal = "Bailliere's Best Practice and Research in Clinical Anaesthesiology",
issn = "1521-6896",
publisher = "Bailliere Tindall Ltd",
number = "2",

}

TY - JOUR

T1 - Physiology of the vasopressin receptors

AU - Maybauer, Marc O.

AU - Maybauer, Dirk M.

AU - Enkhbaatar, Perenlei

AU - Traber, Daniel L.

PY - 2008/6

Y1 - 2008/6

N2 - This review article summarizes the structure, signalling pathways, and tissue distribution of the vasopressin receptors, V1 vascular, V2 renal, V3 pituitary, and oxytocin receptors, as well as the P2 class of purinoceptors. The physiological effects of vasopressin on its receptors are described. The future direction with regard to the role of the V1a receptor in circulatory shock states is discussed; further studies with V1a receptor agonists are warranted to further develop treatment strategies to reduce mortality in life threatening diseases like septic shock.

AB - This review article summarizes the structure, signalling pathways, and tissue distribution of the vasopressin receptors, V1 vascular, V2 renal, V3 pituitary, and oxytocin receptors, as well as the P2 class of purinoceptors. The physiological effects of vasopressin on its receptors are described. The future direction with regard to the role of the V1a receptor in circulatory shock states is discussed; further studies with V1a receptor agonists are warranted to further develop treatment strategies to reduce mortality in life threatening diseases like septic shock.

KW - amino acid sequences

KW - arginine-vasopressin (AVP)

KW - hypovolemia

KW - oxytocin (ot)

KW - sepsis

KW - V1 receptor agonist

KW - vasopressin

KW - vasopressin (VP)

UR - http://www.scopus.com/inward/record.url?scp=44949232034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44949232034&partnerID=8YFLogxK

U2 - 10.1016/j.bpa.2008.03.003

DO - 10.1016/j.bpa.2008.03.003

M3 - Article

VL - 22

SP - 253

EP - 263

JO - Bailliere's Best Practice and Research in Clinical Anaesthesiology

JF - Bailliere's Best Practice and Research in Clinical Anaesthesiology

SN - 1521-6896

IS - 2

ER -