Placental control of drug delivery

Sanaalarab Al-Enazy, Shariq Ali, Norah Albekairi, Marwa El-Tawil, Erik Rytting

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The placenta serves as the interface between the maternal and fetal circulations and regulates the transfer of oxygen, nutrients, and waste products. When exogenous substances are present in the maternal bloodstream-whether from environmental contact, occupational exposure, medication, or drug abuse-the extent to which this exposure affects the fetus is determined by transport and biotransformation processes in the placental barrier. Advances in drug delivery strategies are expected to improve the treatment of maternal and fetal diseases encountered during pregnancy.

Original languageEnglish (US)
JournalAdvanced Drug Delivery Reviews
DOIs
StateAccepted/In press - Jun 14 2016

Fingerprint

Drug and Narcotic Control
Mothers
Fetal Diseases
Waste Products
Occupational Exposure
Biotransformation
Placenta
Substance-Related Disorders
Fetus
Oxygen
Food
Pregnancy
Pharmaceutical Preparations

Keywords

  • Biotransformation
  • Placenta
  • Pregnancy
  • Transporters

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Placental control of drug delivery. / Al-Enazy, Sanaalarab; Ali, Shariq; Albekairi, Norah; El-Tawil, Marwa; Rytting, Erik.

In: Advanced Drug Delivery Reviews, 14.06.2016.

Research output: Contribution to journalArticle

Al-Enazy, Sanaalarab ; Ali, Shariq ; Albekairi, Norah ; El-Tawil, Marwa ; Rytting, Erik. / Placental control of drug delivery. In: Advanced Drug Delivery Reviews. 2016.
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