Plasma insulin-like growth factor I levels during treatment of congenital adrenal hyperplasia

Anita Cavallo, Richard W. Furlanetto, Walter Meyer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We tested the hypotheses that the levels of insulin-like growth factor I (IGF-I) reflect the degree of control during the treatment of patients with congenital adrenal hyperplasia (CAH), and that suppressed IGF-I levels during puberty contribute to decreased adult height. We measured serial IGF-I levels in 26 CAH patients followed over 6 months to 5 years. The control of CAH was variable, with several cases of overtreatment in infancy, and frequent undertreatment in childhood and adolescence. IGF-I levels were quite variable and inconsistent with the control of CAH. Our results suggest that IGF-I levels are not helpful in monitoring CAH patients; IGF-I does not seem to play a role in the growth failure during CAH therapy.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalHormone Research in Paediatrics
Volume34
Issue number1
DOIs
StatePublished - 1990

Fingerprint

Congenital Adrenal Hyperplasia
Insulin-Like Growth Factor I
Therapeutics
Puberty
Growth

Keywords

  • Congenital adrenal hyperplasia
  • Growth
  • Insulin-like growth factor I

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Pediatrics, Perinatology, and Child Health

Cite this

Plasma insulin-like growth factor I levels during treatment of congenital adrenal hyperplasia. / Cavallo, Anita; Furlanetto, Richard W.; Meyer, Walter.

In: Hormone Research in Paediatrics, Vol. 34, No. 1, 1990, p. 23-26.

Research output: Contribution to journalArticle

Cavallo, Anita ; Furlanetto, Richard W. ; Meyer, Walter. / Plasma insulin-like growth factor I levels during treatment of congenital adrenal hyperplasia. In: Hormone Research in Paediatrics. 1990 ; Vol. 34, No. 1. pp. 23-26.
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