Platelet inhibition and anticoagulation in endovascular neurosurgery

Sabih T. Effendi, Sricharan Gopakumar, Peter Kan

Research output: Chapter in Book/Report/Conference proceedingChapter


Achieving an appropriate level of platelet inhibition and anticoagulation is crucial to avoid complications of thrombosis, embolism, and hemorrhage in neuroendovascular procedures. Numerous newer platelet inhibitors and anticoagulants have been released, recently. Additionally, many new laboratory and point-of-care (POC) tests are available on the market to determine the amount of platelet inhibition and anticoagulation. This chapter reviews the most commonly used platelet inhibitors, anticoagulants, and platelet function and anticoagulation tests for neuroendovascular procedures. We also discuss the use of these medications in the most common clinical scenarios.

Original languageEnglish (US)
Title of host publicationIntracranial Aneurysms
Number of pages14
ISBN (Electronic)9780128117408
ISBN (Print)9780128118832
StatePublished - Jan 1 2018
Externally publishedYes


  • Acetylsalicylic acid
  • Anticoagulants
  • Aspirin
  • Clopidogrel
  • Direct factor Xa inhibitors
  • Direct thrombin inhibitors
  • GP IIb/IIIa inhibitors
  • Heparin
  • P2Y12 inhibitors
  • Platelet inhibitors
  • Plavix

ASJC Scopus subject areas

  • General Medicine


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