TY - JOUR
T1 - Pollen NAD(P)H Oxidases and Their Contribution to Allergic Inflammation
AU - Dharajiya, Nilesh G.
AU - Bacsi, Attila
AU - Boldogh, Istvan
AU - Sur, Sanjiv
N1 - Funding Information:
This work was supported by grants from the National Institutes of Health (#1R01 HL071163, SS), the NIAID Program Project Grant (#1P01 AI062885, SS & IB), and the National Heart, Lung, and Blood Institute Proteomics Initiative (#N01-HV28184, SS). The authors do not have any conflicts of interest in terms of relationships with commercial companies.
PY - 2007/2
Y1 - 2007/2
N2 - This article provides an overview of NADPH oxidase and its role in allergic inflammation. A background and historical perspectives of NADPH oxidase are first provided, followed by a detailed overview of mammalian NADPH oxidase subunits and their functional organization. Plant NADPH oxidase, the authors' discovery of NADPH oxidase in pollens, and their contribution to allergic inflammation are then discussed, concluding with a discussion of future directions and outstanding questions that require attention.
AB - This article provides an overview of NADPH oxidase and its role in allergic inflammation. A background and historical perspectives of NADPH oxidase are first provided, followed by a detailed overview of mammalian NADPH oxidase subunits and their functional organization. Plant NADPH oxidase, the authors' discovery of NADPH oxidase in pollens, and their contribution to allergic inflammation are then discussed, concluding with a discussion of future directions and outstanding questions that require attention.
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U2 - 10.1016/j.iac.2006.11.007
DO - 10.1016/j.iac.2006.11.007
M3 - Review article
C2 - 17276878
AN - SCOPUS:33846786788
SN - 0889-8561
VL - 27
SP - 45
EP - 63
JO - Immunology and Allergy Clinics of North America
JF - Immunology and Allergy Clinics of North America
IS - 1
ER -