Pollen NAD(P)H Oxidases and Their Contribution to Allergic Inflammation

Nilesh G. Dharajiya, Attila Bacsi, Istvan Boldogh, Sanjiv Sur

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9 Scopus citations

Abstract

This article provides an overview of NADPH oxidase and its role in allergic inflammation. A background and historical perspectives of NADPH oxidase are first provided, followed by a detailed overview of mammalian NADPH oxidase subunits and their functional organization. Plant NADPH oxidase, the authors' discovery of NADPH oxidase in pollens, and their contribution to allergic inflammation are then discussed, concluding with a discussion of future directions and outstanding questions that require attention.

Original languageEnglish (US)
Pages (from-to)45-63
Number of pages19
JournalImmunology and Allergy Clinics of North America
Volume27
Issue number1
DOIs
StatePublished - Feb 2007

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ASJC Scopus subject areas

  • Immunology and Allergy

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