Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest

Keyphrases

• Ischemia-reperfusion Injury 100%
• Reperfusion 100%
• Poly (ADP-ribose) Polymerase Inhibition 100%
• PJ34 100%
• Hypothermic Cardiac Arrest 100%
• Poly(ADP-ribose) Synthetase 80%
• Coronary Blood Flow 60%
• Acetylcholine 40%
• Sodium Nitroprusside 40%
• Cardiopulmonary Bypass 40%
• Endothelium-dependent Vasodilation 40%
• Endothelial Function 40%
• Myocardial Function 40%
• Ischemia 20%
• DNA Double-strand Breaks 20%
• Cytotoxicity 20%
• Anesthetized Dog 20%
• Free Radical Production 20%
• Metabolic Cycle 20%
• Nicotinamide Adenine Dinucleotide (NAD+) 20%
• Hypothermic Cardiopulmonary Bypass 20%
• Hemodynamic Parameters 20%
• Vehicle Control 20%
• Right Ventricle 20%
• Adenosine Diphosphate 20%
• Left Anterior Descending 20%
• Vasodilator Responses 20%
• Biventricular 20%
• Left Ventricular Systolic Function 20%
• Pressure-volume 20%
• Conductance Catheter 20%
• Afterload 20%
• Right Ventricular Systolic Function 20%
• Inotropic 20%
• Adaptive Potential 20%
• End-systolic Pressure-volume Relation 20%

Medicine and Dentistry

• Poly ADP Ribose Polymerase 100%
• Reperfusion Injury 100%
• N (5,6 Dihydro 6 Oxo 2 Phenanthridinyl) 2 Dimethylaminoacetamide 100%
• Heart Arrest 100%
• Cardiopulmonary Bypass 60%
• Coronary Circulation 60%
• Acetylcholine 40%
• Sodium Nitroprusside 40%
• Endothelial Function 40%
• Vasodilatation 40%
• Myocardial Function 40%
• Cytotoxicity 20%
• Inotropism 20%
• PARP Inhibitor 20%
• DNA Strand Breakage 20%
• Ischemia 20%
• Adenosine Diphosphate 20%
• Hemodynamic 20%
• Right Ventricle 20%
• Systolic Blood Pressure 20%
• Conductance Catheter 20%
• Systolic Function 20%
• Afterload 20%
• Nicotinamide Adenine Dinucleotide 20%
• Table Salt 20%
• Radical (Chemistry) 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 100%
• Reperfusion Injury 100%
• N (5,6 Dihydro 6 Oxo 2 Phenanthridinyl) 2 Dimethylaminoacetamide 100%
• Heart Arrest 100%
• Synthetase 60%
• Poly(adenosine Diphosphate Ribose) 60%
• Nitroprusside Sodium 40%
• Acetylcholine 40%
• Ischemia 20%
• Free Radical 20%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase Inhibitor 20%
• Adenosine Diphosphate 20%
• Cytotoxicity 20%
• Table Salt 20%
• Nicotinamide Adenine Dinucleotide 20%