Polypeptide multilayer films

Donald T. Haynie, Ling Zhang, Jai S. Rudra, Wanhua Zhao, Yang Zhong, Naveen Palath

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

Research on polypeptide multilayer films, coatings, and microcapsules is located at the intersection of several disciplines: synthetic polymer chemistry and physics, biomaterials science, and nanoscale engineering. The past few years have witnessed considerable growth in each of these areas. Unxplored territory has been found at the borders, and new possibilities for technology development are taking form from technological advances in polypeptide production, sequencing of the human genome, and the nature of peptides themselves. Most envisioned applications of polypeptide multilayers have a biomedical bent. Prospects seem no less positive, however, in fields ranging from food technology to environmental science. This review of the present state of polypeptide multilayer film research covers key points of polypeptides as materials, means of polymer production and film preparation, film characterization methods, focal points of current research in basic science, and the outlook for a few specific applications. In addition, it discusses how the study of polypeptide multilayer films could help to clarify the physical basis of assembly and stability of polyelectrolyte multilayers, and mention is made of similarities to protein folding studies.

Original languageEnglish (US)
Pages (from-to)2895-2913
Number of pages19
JournalBiomacromolecules
Volume6
Issue number6
DOIs
StatePublished - Nov 2005
Externally publishedYes

Fingerprint

Polypeptides
Multilayer films
Peptides
Multilayers
Food technology
Polymers
Film preparation
Protein folding
Research
Food Technology
Polyelectrolytes
Biomaterials
Protein Folding
Physics
Biocompatible Materials
Human Genome
Ecology
Capsules
Genes
Coatings

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Haynie, D. T., Zhang, L., Rudra, J. S., Zhao, W., Zhong, Y., & Palath, N. (2005). Polypeptide multilayer films. Biomacromolecules, 6(6), 2895-2913. https://doi.org/10.1021/bm050525p

Polypeptide multilayer films. / Haynie, Donald T.; Zhang, Ling; Rudra, Jai S.; Zhao, Wanhua; Zhong, Yang; Palath, Naveen.

In: Biomacromolecules, Vol. 6, No. 6, 11.2005, p. 2895-2913.

Research output: Contribution to journalArticle

Haynie, DT, Zhang, L, Rudra, JS, Zhao, W, Zhong, Y & Palath, N 2005, 'Polypeptide multilayer films', Biomacromolecules, vol. 6, no. 6, pp. 2895-2913. https://doi.org/10.1021/bm050525p
Haynie DT, Zhang L, Rudra JS, Zhao W, Zhong Y, Palath N. Polypeptide multilayer films. Biomacromolecules. 2005 Nov;6(6):2895-2913. https://doi.org/10.1021/bm050525p
Haynie, Donald T. ; Zhang, Ling ; Rudra, Jai S. ; Zhao, Wanhua ; Zhong, Yang ; Palath, Naveen. / Polypeptide multilayer films. In: Biomacromolecules. 2005 ; Vol. 6, No. 6. pp. 2895-2913.
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