Positional assignment of differentially substituted bisaminoacylated pdCpAs

David J. Maloney; Noha Ghanem; Jia Zhou; Sidney M. Hecht

doi:10.1039/b708786a

Positional assignment of differentially substituted bisaminoacylated pdCpAs

David J. Maloney, Noha Ghanem, Jia Zhou, Sidney M. Hecht

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- ¹³C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

Original language	English (US)
Pages (from-to)	3135-3138
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	5
Issue number	19
DOIs	https://doi.org/10.1039/b708786a
State	Published - Sep 25 2007
Externally published	Yes

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ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Cite this

Maloney, D. J., Ghanem, N., Zhou, J., & Hecht, S. M. (2007). Positional assignment of differentially substituted bisaminoacylated pdCpAs. Organic and Biomolecular Chemistry, 5(19), 3135-3138. https://doi.org/10.1039/b708786a

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abstract = "The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- 13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.",

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Access to Document

10.1039/b708786a