Positional assignment of differentially substituted bisaminoacylated pdCpAs

David J. Maloney, Noha Ghanem, Jia Zhou, Sidney M. Hecht

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- 13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

Original languageEnglish (US)
Pages (from-to)3135-3138
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number19
DOIs
StatePublished - 2007

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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