Positional assignment of differentially substituted bisaminoacylated pdCpAs

David J. Maloney; Noha Ghanem; Jia Zhou; Sidney M. Hecht

doi:10.1039/b708786a

Positional assignment of differentially substituted bisaminoacylated pdCpAs

David J. Maloney, Noha Ghanem, Jia Zhou, Sidney M. Hecht

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- ¹³C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

Original language	English (US)
Pages (from-to)	3135-3138
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	5
Issue number	19
DOIs	https://doi.org/10.1039/b708786a
State	Published - 2007
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/b708786a

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title = "Positional assignment of differentially substituted bisaminoacylated pdCpAs",

abstract = "The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- 13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.",

author = "Maloney, {David J.} and Noha Ghanem and Jia Zhou and Hecht, {Sidney M.}",

year = "2007",

doi = "10.1039/b708786a",

language = "English (US)",

volume = "5",

pages = "3135--3138",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

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T1 - Positional assignment of differentially substituted bisaminoacylated pdCpAs

AU - Maloney, David J.

AU - Ghanem, Noha

AU - Zhou, Jia

AU - Hecht, Sidney M.

PY - 2007

Y1 - 2007

N2 - The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- 13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

AB - The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- 13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

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U2 - 10.1039/b708786a

DO - 10.1039/b708786a

M3 - Article

C2 - 17878972

AN - SCOPUS:34548761899

VL - 5

SP - 3135

EP - 3138

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 19

ER -

Positional assignment of differentially substituted bisaminoacylated pdCpAs

Abstract

ASJC Scopus subject areas

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