Positron emission tomography imaging in evaluation of cancer patients

R. Kumar, Peeyush Bhargava, M. F. Bozkurt, H. Zhuang, S. Potenta, A. Alavi

Research output: Contribution to journalReview article

27 Scopus citations

Abstract

Positron emission tomography (PET) is a diagnostic imaging technique that has progressed rapidly from being a research technique in laboratories to a routine clinical imaging modality. The most widely used radiotracer in PET is Fluorine18-fluorodeoxyglucose (F18-FDG), which is an analogue of glucose. The FDG uptake in cells is directly proportional to glucose metabolism of cells. Since glucose metabolism is increased many fold in malignant tumors PET has a high sensitivity and a high negative predictive value. PET with FDG is now the standard of care in initial staging, monitoring the response to the therapy, and management of lung cancer, colonic cancer, lymphoma, melanoma, esophageal cancer, head and neck cancer and breast cancer. Other indications of PET like bone tumor, ovarian cancer and cancer of unknown primary (CUP) has also been discussed in brief. The aim of this review article is to review the clinical applications of PET in various malignancies and only limited number of important studies will be discussed for this effort.

Original languageEnglish (US)
Pages (from-to)87-100
Number of pages14
JournalIndian Journal of Cancer
Volume40
Issue number3
StatePublished - Jul 1 2003
Externally publishedYes

Keywords

  • Breast cancer
  • Colonic cancer
  • Fluorodeoxyglucose
  • Gastric and esophageal cancer
  • Head and neck cancer
  • Lung nodule and lung cancer
  • Lymphoma
  • Melanoma
  • Ovarian cancer
  • Positron emission tomography

ASJC Scopus subject areas

  • Oncology

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  • Cite this

    Kumar, R., Bhargava, P., Bozkurt, M. F., Zhuang, H., Potenta, S., & Alavi, A. (2003). Positron emission tomography imaging in evaluation of cancer patients. Indian Journal of Cancer, 40(3), 87-100.