Postsurgical IQ and behavioral data on twenty patients with a history of childhood craniopharyngioma

Richard R. Clopper; Walter J. Meyer; George B. Udvarhelyi; John Money; Bizhan Aarabi; John J. Mulvihill; Mark Piasio

doi:10.1016/0306-4530(77)90006-3

Postsurgical IQ and behavioral data on twenty patients with a history of childhood craniopharyngioma

Richard R. Clopper, Walter J. Meyer, George B. Udvarhelyi, John Money, Bizhan Aarabi, John J. Mulvihill, Mark Piasio

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

(1) Postsurgical data on IQ, psychosocial and psychosexual function is presented on twenty patients with a history of childhood or teenage craniopharyngioma. (2) A specific deficit in Performance as compared with Verbal IQ was observed even though Full Scale IQ was no different from the test norms. (3) Social isolation, low energy expenditure and diminished frequencies of erotic behavior were typical features of these patients even though appropriate hormonal replacement was given postsurgically. (4) Deficits in hypothalamic pathways and/or the effects of protracted social isolation appear to be more important for the development of psychosexual behavior in hypopituitary patients than is postpubertal hormonal status.

Original language	English (US)
Pages (from-to)	365-372
Number of pages	8
Journal	Psychoneuroendocrinology
Volume	2
Issue number	4
DOIs	https://doi.org/10.1016/0306-4530(77)90006-3
State	Published - 1977
Externally published	Yes

Keywords

IQ
behavior
childhood
craniopharyngioma

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Psychiatry and Mental health
Biological Psychiatry

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10.1016/0306-4530(77)90006-3

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@article{326304aabfc147e08c6d80131b1911d7,

title = "Postsurgical IQ and behavioral data on twenty patients with a history of childhood craniopharyngioma",

abstract = "(1) Postsurgical data on IQ, psychosocial and psychosexual function is presented on twenty patients with a history of childhood or teenage craniopharyngioma. (2) A specific deficit in Performance as compared with Verbal IQ was observed even though Full Scale IQ was no different from the test norms. (3) Social isolation, low energy expenditure and diminished frequencies of erotic behavior were typical features of these patients even though appropriate hormonal replacement was given postsurgically. (4) Deficits in hypothalamic pathways and/or the effects of protracted social isolation appear to be more important for the development of psychosexual behavior in hypopituitary patients than is postpubertal hormonal status.",

keywords = "IQ, behavior, childhood, craniopharyngioma",

author = "Clopper, {Richard R.} and Meyer, {Walter J.} and Udvarhelyi, {George B.} and John Money and Bizhan Aarabi and Mulvihill, {John J.} and Mark Piasio",

note = "Funding Information: The authors gratefully acknowledge the valuable assistance of Florence C. Clarke with data collection. Supported by USPHS Grant I-ID00325, The Grant Foundation, Inc., New York. The patients were studied at the Clinical Research Center of The Department of Pediatrics, The Johns Hopkins University, supported",

year = "1977",

doi = "10.1016/0306-4530(77)90006-3",

language = "English (US)",

volume = "2",

pages = "365--372",

journal = "Psychoneuroendocrinology",

issn = "0306-4530",

publisher = "Elsevier Ltd",

number = "4",

}

TY - JOUR

T1 - Postsurgical IQ and behavioral data on twenty patients with a history of childhood craniopharyngioma

AU - Clopper, Richard R.

AU - Meyer, Walter J.

AU - Udvarhelyi, George B.

AU - Money, John

AU - Aarabi, Bizhan

AU - Mulvihill, John J.

AU - Piasio, Mark

N1 - Funding Information: The authors gratefully acknowledge the valuable assistance of Florence C. Clarke with data collection. Supported by USPHS Grant I-ID00325, The Grant Foundation, Inc., New York. The patients were studied at the Clinical Research Center of The Department of Pediatrics, The Johns Hopkins University, supported

PY - 1977

Y1 - 1977

N2 - (1) Postsurgical data on IQ, psychosocial and psychosexual function is presented on twenty patients with a history of childhood or teenage craniopharyngioma. (2) A specific deficit in Performance as compared with Verbal IQ was observed even though Full Scale IQ was no different from the test norms. (3) Social isolation, low energy expenditure and diminished frequencies of erotic behavior were typical features of these patients even though appropriate hormonal replacement was given postsurgically. (4) Deficits in hypothalamic pathways and/or the effects of protracted social isolation appear to be more important for the development of psychosexual behavior in hypopituitary patients than is postpubertal hormonal status.

AB - (1) Postsurgical data on IQ, psychosocial and psychosexual function is presented on twenty patients with a history of childhood or teenage craniopharyngioma. (2) A specific deficit in Performance as compared with Verbal IQ was observed even though Full Scale IQ was no different from the test norms. (3) Social isolation, low energy expenditure and diminished frequencies of erotic behavior were typical features of these patients even though appropriate hormonal replacement was given postsurgically. (4) Deficits in hypothalamic pathways and/or the effects of protracted social isolation appear to be more important for the development of psychosexual behavior in hypopituitary patients than is postpubertal hormonal status.

KW - IQ

KW - behavior

KW - childhood

KW - craniopharyngioma

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DO - 10.1016/0306-4530(77)90006-3

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AN - SCOPUS:0017592042

SN - 0306-4530

VL - 2

SP - 365

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JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

IS - 4

ER -

Postsurgical IQ and behavioral data on twenty patients with a history of childhood craniopharyngioma

Abstract

Keywords

ASJC Scopus subject areas

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