Potential Mechanisms for Enhanced Zika Epidemic and Disease

Hongjie Xia, Xuping Xie, Chao Shan, Pei-Yong Shi

Research output: Contribution to journalReview article

4 Scopus citations


A number of mechanisms have driven the explosive epidemics and severe diseases of Zika virus since 2007. Here, we comment on how herd immunity, heterologous flavivirus preimmunity, and viral mutations could enhance the epidemic potential and disease severity of Zika virus in humans.

Original languageEnglish (US)
Pages (from-to)656-659
Number of pages4
JournalACS Infectious Diseases
Issue number5
StatePublished - May 11 2018


ASJC Scopus subject areas

  • Infectious Diseases

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